Anti-immunoglobulin-induced Apoptosis in WEHI 231 Cells Involves the Slow Formation of Ceramide from Sphingomyelin and Is Blocked by bcl-xL

Douglas A. Wiesner, John Kilkus, Alexander Gottschalk, +2

Journal of Biological Chemistry

Absence of oligodendroglial glucosylceramide synthesis does not result in CNS myelin abnormalities or alter the dysmyelinating phenotype of CGT‐deficient mice

Laleh Saadat, Jeffrey L. Dupree, John Kilkus, +4

Glia

Ceramide in rafts (detergent‐insoluble fraction) mediates cell death in neurotumor cell lines

John Kilkus, Rajendra Goswami, Fernando D. Testai, +1

Journal of Neuroscience Research

Multiple sphingolipid abnormalities following cerebral microendothelial hypoxia

Fernando D. Testai, John Kilkus, Evgeny Berdyshev, +2

Journal of Neurochemistry

Lipid PeroxidationRedox BiologyOxidative StressCerebral Vascular RegulationNeurovascular Disease +23

Resistance to anti‐IgM‐induced apoptosis in a WEHI‐231 subline is due to insufficient production of ceramide

Alexander Gottschalk, Carol L. McShan, John Kilkus, +2

European Journal of Immunology

Connecting Exosomes and Connexins

Joanna Gemel, John Kilkus, Glyn Dawson, +1

Cancers

Protein SecretionMolecular BiologyExtracellular MicrovesiclesCytoskeletonCell Junctions +15

Mitochondrial abnormalities in CLN2 and CLN3 forms of batten disease

Glyn Dawson, John Kilkus, A. N. Siakotos, +1

Molecular and Chemical Neuropathology

Mitochondrial AbnormalitiesDisease MechanismMitochondrial FunctionGeneticsPathogenesis +5

Changes in the metabolism of sphingolipids after subarachnoid hemorrhage

Fernando D. Testai, Hao‐Liang Xu, John Kilkus, +4

Journal of Neuroscience Research

Sms ActivitiesCell DeathOxidative StressNeuroinflammationCerebral Vascular Regulation +19

Oxidized phosphatidylcholine formation and action in oligodendrocytes

Jingdong Qin, Fernando D. Testai, Sylvia Dawson, +2

Journal of Neurochemistry

Neutral SphingomyelinaseLipid PeroxidationApoptosisCell DeathLipid Movement +20

The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator—role of Ceramide in MU anti-tumor activity

Jingdong Qin, John Kilkus, Glyn Dawson

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

OncologyMedicineMu Anti-tumor ActivityCancer Cell BiologyPathology +9