Casey Capparelli

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Young‐Yun Kong, Hiroki Yoshida, Ildiko Sarosi et al. · Nature · 1999 · 3.3K citations

Developmental Biology, Key Regulator, Bone Morphogenic Protein +11

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young‐Yun Kong, Ulrich Feige, Iidiko Sarosi et al. · Nature · 1999 · 1.9K citations

Inflammation, Rheumatology, Rheumatoid Disorder +14

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

Hailing Hsu, David L. Lacey, Colin R. Dunstan et al. · Proceedings of the National Academy of Sciences · 1999 · 1.6K citations · Full text

Inflammation, Osteoprotegerin Ligand, Sclerostin +14

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

Ji Li, Ildiko Sarosi, Xiaoqiang Yan et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations · Full text

Osteoprotegerin Reverses Osteoporosis by Inhibiting Endosteal Osteoclasts and Prevents Vascular Calcification by Blocking a Process Resembling Osteoclastogenesis

Hosung Min, Sean Morony, Ildiko Sarosi et al. · The Journal of Experimental Medicine · 2000 · 555 citations · Full text

Sclerostin, Osteoporosis, Orthopaedic Surgery +17