Establishment of methylation-sensitive–representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors

Toshikazu Ushijima, Keiichirou Morimura, Yoko Hosoya, +4

Proceedings of the National Academy of Sciences

Altered expression of several genes in highly metastatic subpopulations of a human pulmonary adenocarcinoma cell line

Akihiko Gemma, K. Takenaka, Yoko Hosoya, +10

European Journal of Cancer

Altered ExpressionMetastatic SubpopulationsTumor HeterogeneityMedicinePathology +9

Aberrations in the fragile histidine triad (FHIT) gene in idiopathic pulmonary fibrosis.

Kazutsugu Uematsu, Atsunori Yoshimura, Akihiko Gemma, +13

PubMed

Lung InflammationGeneticsMolecular BiologyPathologyPulmonary Alveolar Proteinosis +16

Increase in the frequency of p16INK4 gene inactivation by hypermethylation in lung cancer during the process of metastasis and its relation to the status of p53.

Masahiro Seike, Akihiko Gemma, Yoko Hosoya, +5

PubMed

GeneticsPathologyCancer BiologyEpigeneticsTumor Biology +14

Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers

Akihiko Gemma, Yoko Hosoya, Masahiro Seike, +7

Lung Cancer

Somatic VariantOncogenic AgentHuman Mad2 GeneGeneticsMedicine +7

Increased expression of the <i>LGALS3</i> (<i>Galectin 3</i>) gene in human non–small‐cell lung cancer

Akinobu Yoshimura, Akihiko Gemma, Yoko Hosoya, +12

Genes Chromosomes and Cancer

Tumor BiologyGalectin 3MedicineMetastatic Cell LinesImmunology +12

A rat genetic map constructed by representational difference analysis markers with suitability for large-scale typing.

M Toyota, Federico Canzian, Toshikazu Ushijima, +6

Proceedings of the National Academy of Sciences

CytogeneticsGeneticsHuman PolymorphismMolecular GeneticsGenomics +17

Alterations in novel candidate tumor suppressor genes, ING1 and ING2 in human lung cancer

Tetsuya Okano, Akihiko Gemma, Yoko Hosoya, +8

Oncology Reports

Tissue-specific mutational spectra of 2-amino-3,4-dimethylimidazo[4,5-<i>f</i>]quinoline in the liver and bone marrow of <i>lacl</i> transgenic mice

Toshikazu Ushijima, Yoko Hosoya, Masako Ochiai, +7

Carcinogenesis

EngineeringGeneticsPathologyMolecular BiologyMolecular Genetics +14

Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Minoru Toyota, Toshikazu Ushijima, John H. Weisburger, +6

Molecular Carcinogenesis

Genome InstabilitySomatic VariantTumor HeterogeneityCytogeneticsGenetics +12