Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Laura A. Solt, Yongjun Wang, Subhashis Banerjee, +11

Nature

Energy HomeostasisSleepSystems BiologyAlertnessMedicine +11

Phenylarsine oxide inhibition of endocytosis: effects on asialofetuin internalization

Adele Gibson, Romain Noël, Jeremiah T. Herlihy, +1

American Journal of Physiology-Cell Physiology

Metabolic RemodelingProtein InternalizationRedox BiologyOxidative StressBioenergetics +17

<i>N</i>-Methyldihydroquinazolinone Derivatives of Retro-2 with Enhanced Efficacy against Shiga Toxin

Romain Noël, Neetu Gupta, Valérie Pons, +9

Journal of Medicinal Chemistry

Retro-2 MoleculeMedicinal ChemistryPharmaceutical ChemistryBiochemistryMedicine +10

Secondary Valence Force Catalysis. II. Kinetics of the Hydrolysis of Orthoesters and the Hydrolysis and Aminolysis of Carboxylic Esters in the Presence of Micelle-Forming Detergents¹

Margaret T. Behme, J. G. Fullington, Romain Noël, +1

Journal of the American Chemical Society

EngineeringBiochemistryDonut IconNatural SciencesEnzyme Catalysis +11

The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

Xin Ming, Kyle Carver, Michael Fisher, +7

Nucleic Acids Research

Small Molecule Retro-1Natural SciencesCompound Retro-1Dna ReplicationSynthetic Biology +13

Organocatalysed multicomponent synthesis of pyrazolidinones: Meldrum's acid approach

Etienne Pair, Christophe Berini, Romain Noël, +3

Chemical Communications

Novel OrganocatalystsEngineeringHeterocyclicNatural SciencesAcid Approach +9

(<i>S</i>)-<i>N</i>-Methyldihydroquinazolinones are the Active Enantiomers of Retro-2 Derived Compounds against Toxins

Neetu Gupta, Valérie Pons, Romain Noël, +6

ACS Medicinal Chemistry Letters

Retrograde RouteMedicinal ChemistryPharmaceutical ScienceNew CompoundBiochemistry +12

Retro-2 and its dihydroquinazolinone derivatives inhibit filovirus infection

Olena Shtanko, Yasuteru Sakurai, Ann Reyes, +5

Antiviral Research

Microbial PathogensMedicineFilovirus InfectionImmunologyAntiviral Response +10

Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales

Neetu Gupta, Romain Noël, Amélie Goudet, +28

Chemico-Biological Interactions

Antiparasitic AgentShiga ToxinsPathogenesisImmunologyAntiviral Drug Development +6

Subsarcolemmal and interfibrillar mitochondria display distinct superoxide production profiles

Clément Crochemore, Malik Mekki, Cécile Corbière, +5

Free Radical Research

Interfibrillar MitochondriaSuperoxide GenerationBiochemistryMitochondrial FunctionComplex Iii +9