Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness

Bernhard W. Renz, Takayuki Tanaka, Masaki Sunagawa, +22

Cancer Discovery

SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway

Shan Tian, Pailan Peng, Jiao Li, +4

Aging

Gc ProgressionPathologyCancer BiologyTumor BiologyOncology +15

Vascular Cytochrome P450 4A Expression and 20-Hydroxyeicosatetraenoic Acid Synthesis Contribute to Endothelial Dysfunction in Androgen-Induced Hypertension

Harpreet Singh, Jennifer Cheng, Huan Deng, +4

Hypertension

HypertensionBlood PressureOxidative StressMolecular PharmacologyMetabolic Syndrome +14

Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

Weijun Feng, Daisuke Kawauchi, Huiqin Körkel-Qu, +23

Nature Communications

Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop

Xiaowei Chen, Huan Deng, Michael Churchill, +32

Cell stem cell

Hematological MalignancyHistamine-dependent Feedback LoopBone Marrow FailureMedicineStem Cell Mobilization +9

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

Wenju Chang, Hongshan Wang, Woosook Kim, +13

Cell stem cell

Embryonic Stem CellGastric TumorigenesisDevelopmental BiologyCell DivisionMedicine +9

Prophylaxis against carcinogenesis in three kinds of unestablished tumor models via IL12-gene-engineered MSCs

Xin Chen, Ruojun Wang, Xinshu Zhao, +18

Carcinogenesis

Mesenchymal Stem CellsTumor BiologyOncogenic AgentMedicineStem Cells +12

Paranuclear Dot-like Immunostaining for CD99

Yan Guo, Fei Yuan, Huan Deng, +3

The American Journal of Surgical Pathology

Tumoral PathologyPancreatic CancerPseudopapillary StructuresMedicineSolid-pseudopapillary Neoplasm Cells +11

Cancer-associated adipocyte-derived G-CSF promotes breast cancer malignancy via Stat3 signaling

Li Liu, Yudong Wu, Cheng Zhang, +14

Journal of Molecular Cell Biology

Cancer ResearchBreast OncologySignaling PathwayMedicineImmunology +13

Inhibition of Glycogen Synthase Kinase-3β Is Sufficient for Airway Smooth Muscle Hypertrophy

Huan Deng, Gregoriy A. Dokshin, Jing Lei, +5

Journal of Biological Chemistry

AsthmaMuscle FunctionMolecular PhysiologyPhysiologyPulmonary Pharmacology +5