An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation

Hidesaku Asakura, Yasuo Ontachi, Tomoe Mizutani, +7

Critical Care Medicine

Decreased plasma activity of antithrombin or protein C is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation

Hidesaku Asakura, Yasuo Ontachi, Tomoe Mizutani, +11

European Journal Of Haematology

Pathophysiology of disseminated intravascular coagulation (DIC) progresses at a different rate in tissue factor-induced and lipopolysaccharide-induced DIC models in rats

Hidesaku Asakura, Yukio Suga, Tomotaka Yoshida, +8

Blood Coagulation & Fibrinolysis

ImmunologyDifferent RateInflammationThrombosisHematology +20

Marked difference in pathophysiology between tissue factor- and lipopolysaccharide-induced disseminated intravascular coagulation models in rats

Hidesaku Asakura, Yukio Suga, Keiji Aoshima, +9

Critical Care Medicine

Vitamin K Administration to Elderly Patients with Osteoporosis Induces No Hemostatic Activation, Even in Those with Suspected Vitamin K Deficiency

Hidesaku Asakura, Shigeharu Myou, Yasuo Ontachi, +6

Osteoporosis International

Vitamin K AntagonistsBone DiseaseBone HealthElderly PatientsHematology +6

Elevated levels of free tissue factor pathway inhibitor antigen in cases of disseminated intravascular coagulation caused by various underlying diseases

Hidesaku Asakura, Yasuo Ontachi, Tomoe Mizutani, +7

Blood Coagulation & Fibrinolysis

Vascular DiseaseEndothelial CellsImmunologyPathologyInflammation +20

Beneficial effect of low-molecular-weight heparin against lipopolysaccharide-induced disseminated intravascular coagulation in rats is abolished by coadministration of tranexamic acid

Hidesaku Asakura, Yoko Sano, Tomotaka Yoshida, +8

Intensive Care Medicine

InflammationThrombosisBlood PlateletMedicineBeneficial Effect +12

Prednisolone inhibits endotoxin-induced disseminated intravascular coagulation and improves mortality in rats

M. Yamazaki, Keiji Aoshima, Tomoe Mizutani, +6

Blood Coagulation & Fibrinolysis

ImmunologyCell DeathPharmacotherapyInflammationThrombosis +16

Depressed plasma activity of plasminogen or α2 plasmin inhibitor is not due to consumption coagulopathy in septic patients with disseminated intravascular coagulation

Hidesaku Asakura, Yasuo Ontachi, Tomoe Mizutani, +7

Blood Coagulation & Fibrinolysis

Significance of Decreased Plasma D-Dimer Levels following Lipopolysaccharide-Induced Disseminated Intravascular Coagulation in Rats

Hidesaku Asakura, Yoko Sano, Mika Omote, +9

International Journal of Hematology

InflammationThrombosisVascular DiseaseCardiovascular DiseaseMedicine +9