3,5-Dioxopyrazolidines, Novel Inhibitors of UDP- <i>N</i> - Acetylenolpyruvylglucosamine Reductase (MurB) with Activity against Gram-Positive Bacteria

Youjun Yang, Anatoly Severin, Rajiv Chopra, +14

Antimicrobial Agents and Chemotherapy

4-Alkyl and 4,4′-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis

Kristina M. K. Kutterer, Jamie M. Davis, Guy Singh, +7

Bioorganic & Medicinal Chemistry Letters

BiosynthesisAntimicrobial Drug DiscoveryMedicineNew InhibitorsAntibacterial Agent +5

Pyridobenzodiazepines: A novel class of orally active, vasopressin V2 receptor selective agonists

Amedeo Failli, Jay S. Shumsky, Robert J. Steffan, +9

Bioorganic & Medicinal Chemistry Letters

Functional SelectivityMedicinePsychotropic MedicationPhysiologyMechanism Of Action +6

Synthetic entries to 6‐fluoro‐7‐substituted indole derivatives

Brian A. McKittrick, Amedeo Failli, Robert J. Steffan, +7

Journal of Heterocyclic Chemistry

Diversity Oriented SynthesisDerivative (Chemistry)DerivativesIndole TemplateBiochemistry +12

Use of Structure-Based Drug Design Approaches to Obtain Novel Anthranilic Acid Acyl Carrier Protein Synthase Inhibitors

Diane Joseph‐McCarthy, Kevin Parris, Adrian Huang, +14

Journal of Medicinal Chemistry

Combinatorial ChemistryMolecular BiologyChemical BiologyBiosynthesisDrug Design +20

Total Synthesis of Indole and Dihydroindole Alkaloids. VI. The total synthesis of some monomeric vinca alkaloids: dl‐Vincadine, dl‐vincaminoreine, dl‐vincaminorine, dl‐vincadifformine, dl‐minovine and dl‐vincaminoridine

James P. Kutney, Ka Kong Chan, Amedeo Failli, +5

Helvetica Chimica Acta

Combinatorial ChemistryDiversity Oriented SynthesisBiosynthesisBiochemistryDihydroindole Alkaloids +13

Total synthesis of some monomeric Vinca alkaloids: dl-vincadine, dl-vincaminoreine, dl-vincaminorine, dl-vincadifformine, dl-minovine, and dl-vincaminoridine

James P. Kutney, Ka Kong Chan, Amedeo Failli, +3

Journal of the American Chemical Society

Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicine +12

Base catalyzed degradations of rapamycin

Robert J. Steffan, Robert M. Kearney, David C.K. Hu, +6

Tetrahedron Letters

Natural SciencesBiocatalysisBiochemistry

Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists

Aimee L. Crombie, Thomas M. Antrilli, Brandon A. Campbell, +7

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryHeterocyclicMedicineOrganic ChemistryPharmacotherapy +5

Advances toward New Antidepressants with Dual Serotonin Transporter and 5-HT_1AReceptor Affinity within a Class of 3-Aminochroman Derivatives. Part 2

Nicole T. Hatzenbuhler, Reinhardt B Baudy, Deborah A. Evrard, +18

Journal of Medicinal Chemistry

Combinatorial ChemistryNew AntidepressantsPsychotropic MedicationPsychopharmacologyPharmacotherapy +19