K. Uma

Alpha-helix and mixed 3(10)/alpha-helix in cocrystallized conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-OMe.

Isabella L. Karle, J.L. Flippen-Anderson, K. Uma et al. · Proceedings of the National Academy of Sciences · 1989 · 71 citations · Full text

Materials Science, Crystal Structure, Engineering +15

Apolar peptide models for conformational heterogeneity, hydration, and packing of polypeptide helices: Crystal structure of hepta‐ and octapeptides containing α‐aminoisobutyric acid

Isabella L. Karle, J.L. Flippen-Anderson, K. Uma et al. · Proteins Structure Function and Bioinformatics · 1990 · 65 citations

Modular design of synthetic protein mimics. Crystal structure of two seven-residue helical peptide segments linked by .epsilon.-aminocaproic acid

Isabella L. Karle, J.L. Flippen-Anderson, M. Sukumar et al. · Journal of the American Chemical Society · 1991 · 60 citations

Synthetic Protein Mimics, Crystal Structure, Protein Assembly +18

Unfolding of an α‐helix in peptide crystals by solvation: Conformational fragility in a heptapeptide

Isabella L. Karle, J.L. Flippen-Anderson, K. Uma et al. · Biopolymers · 1993 · 58 citations

Aqueous channels within apolar peptide aggregates: solvated helix of the alpha-aminoisobutyric acid (Aib)-containing peptide Boc-(Aib-Ala-Leu)3-Aib-OMe.2H2O.CH3OH in crystals.

Isabella L. Karle, Judith Flippen‐Anderson, K. Uma et al. · Proceedings of the National Academy of Sciences · 1988 · 52 citations · Full text

Protein Assembly, Peptide Engineering, Apolar Peptide Aggregates +17