Testosterone Perturbs Systemic Iron Balance Through Activation of Epidermal Growth Factor Receptor Signaling in the Liver and Repression of Hepcidin

Chloé Latour, Léon Kautz, Céline Besson‐Fournier, +6

Hepatology

Purification of neuronal inclusions of patients with Huntington's disease reveals a broad range of N‐terminal fragments of expanded huntingtin and insoluble polymers

Guylaine Hoffner, Marie‐Laure Island, Philippe Djian

Journal of Neurochemistry

A novel N491S mutation in the human SLC11A2 gene impairs protein trafficking and in association with the G212V mutation leads to microcytic anemia and liver iron overload

Edouard Bardou‐Jacquet, Marie‐Laure Island, Anne‐Marie Jouanolle, +8

Blood Cells Molecules and Diseases

G212v MutationGenetic DisorderLiver Iron OverloadGeneticsMedicine +6

Ferroportin Diseases: Functional Studies, a Link Between Genetic and Clinical Phenotype

Lénaı̈ck Détivaud, Marie‐Laure Island, Anne‐Marie Jouanolle, +9

Human Mutation

Functional StudiesFpn Gene MutationGeneticsGenetic EpidemiologyPathology +22

Simulated microgravity disturbs iron metabolism and distribution in humans: Lessons from dry immersion, an innovative ground‐based human model

Kévin Nay, Christelle Koechlin‐Ramonatxo, Sarah Rochdi, +9

The FASEB Journal

NutritionIron MetabolismIron DeficiencyNutrient BioavailabilityBody Composition +15

Silencer Activity in the Interferon-A Gene Promoters

S. Lopez, Raymond Reeves, Marie‐Laure Island, +4

Journal of Biological Chemistry

Transcriptional RegulationSystems BiologyCentral RegionViral ReplicationMedicine +13

Repression by Homeoprotein Pitx1 of Virus-Induced Interferon A Promoters Is Mediated by Physical Interaction and <i>trans</i> Repression of IRF3 and IRF7

Marie‐Laure Island, Thibault Mésplède, Nicole Darracq, +5

Molecular and Cellular Biology

Molecular RegulationGeneticsImmunologyPhysical InteractionGene Regulatory Network +17

GATA-4 transcription factor regulates hepatic hepcidin expression

Marie‐Laure Island, Nadia Fatih, Patricia Leroyer, +2

Biochemical Journal

Iron MetabolismTranscriptional RegulationHepcidin Gene ExpressionProtein ExpressionIron Bioavailability +15

Mouse genetic background impacts both on iron and non-iron metals parameters and on their relationships

Thibault Cavey, Martine Ropert, Marie de Tayrac, +6

BioMetals

BiologyKnockout MouseIron MetabolismGeneticsBioactive Metal +8

Repression of Virus-Induced Interferon A Promoters by Homeodomain Transcription Factor Ptx1

S. Lopez, Marie‐Laure Island, Jacques Drouin, +7

Molecular and Cellular Biology