Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, +1267

Autophagy

Characterization and Implications of Estrogenic Down-Regulation of Human Catechol-<i>O</i>-Methyltransferase Gene Transcription

Tao Xie, Shu‐Leong Ho, D. Ramsden

Molecular Pharmacology

Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)

Philip Wing‐Lok Ho, Chi-Ting Leung, Huifang Liu, +7

Autophagy

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

Genta Ito, Kristina Katsemonova, Francesca Tonelli, +8

Biochemical Journal

Signal RecognitionMolecular BiologyPhos-tag AnalysisMajor Rab10 KinaseCell Regulation +17

Development of phospho-specific Rab protein antibodies to monitor <i>in vivo</i> activity of the LRRK2 Parkinson's disease kinase

Sophie Burel, Martin Steger, Matthias Mann, +11

Biochemical Journal

Predicting Mendelian Disease-Causing Non-Synonymous Single Nucleotide Variants in Exome Sequencing Studies

Miaoxin Li, Johnny S. H. Kwan, Suying Bao, +4

PLoS Genetics

Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction

D. Ramsden, Philip Wing‐Lok Ho, Jessica W.‐M. Ho, +5

Brain and Behavior

Human Neuronal UncouplingProtein Quality ControlMitochondrial FunctionBiochemistryMitochondrial Dysfunction +13

Emotion recognition in patients with idiopathic Parkinson's disease

James T. H. Yip, Tatia M.C. Lee, Shu‐Leong Ho, +2

Movement Disorders

NeuropsychologyBrain FunctionAffective NeuroscienceClinical NeurologyNeuropsychiatry +23

Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2^R1441Gmice

Huifang Liu, Philip Wing‐Lok Ho, Chi-Ting Leung, +6

Autophagy

Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease

Philip Wing‐Lok Ho, Jessica W.‐M. Ho, Huifang Liu, +5

Translational Neurodegeneration