alpha-Naphthoflavone-induced CYP1A1 gene expression and cytosolic aryl hydrocarbon receptor transformation.

Michael J. Santostefano, Mark Merchant, Luis Armando De la Peña Arellano, +3

Molecular Pharmacology

GW627368X ((<i>N</i>‐{2‐[4‐(4,9‐diethoxy‐1‐oxo‐1,3‐dihydro‐2<i>H</i>‐benzo[<i>f</i>]isoindol‐2‐yl)phenyl]acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP₄ receptor antagonist

Richard J. Wilson, Gerard M.P. Giblin, Susan Roomans, +14

British Journal of Pharmacology

Molecular PharmacologyAntagonist AffinitySelective Competitive AntagonistBiochemistryFunctional Selectivity +11

A preliminary evaluation of the performance of the Muta^TM Mouse (<i>lacZ</i>) and Big Blue^TM (<i>lacl</i>) transgenic mouse mutation assays

V. Morrison, J. Ashby

Mutagenesis

Mechanism of action of aryl hydrocarbon receptor antagonists: Inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression

Mark Merchant, V. Morrison, Michael J. Santostefano, +1

Archives of Biochemistry and Biophysics

BiochemistryFunctional SelectivityMedicineMechanism Of ActionReceptor (Biochemistry) +4

6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) is an antiestrogen in human and rodent cancer cell lines: Evidence for the role of the Ah receptor

T. Zachrewski, Mark Anglin Harris, Lisa B. Biegel, +3

Toxicology and Applied Pharmacology

OncologyOncogenic AgentMedicinePathologyAh Receptor +4

Role of specific cytochrome P-450 isoenzymes in the regio-selective metabolism of 7, 12-dimethylbenz[<i>a</i>]anthracene in microsomes from rats treated with phenobarbital or Sudan III

Anne McCord, Alan K. Burnett, C. Roland Wolf, +2

Carcinogenesis

Sudan IiiMolecular PharmacologyDmba-microsome AdductsAdduct FormationBiochemistry +13

Mechanism of benzo[a]pyrene-induced Cyp1a-1 gene expression in mouse Hepa 1c1c7 cells: Role of the nuclear 6 s and 4 s proteins

Mark Merchant, Xiaofang Wang, C. Kamps, +3

Archives of Biochemistry and Biophysics

Signal TransductionSignaling PathwayMolecular PathwayS ProteinsLiver Physiology +10

The contribution of specific cytochromes P-450 in the metabolism of 7,12-dimethylbenz[a]anthracene in rat and human liver microsomal membranes

V. Morrison, Alan K. Burnett, Lesley M. Forrester, +2

Chemico-Biological Interactions

BiochemistryMedicineLiver PhysiologyToxicologyHepatotoxicity +8

Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: Characterization of 6-[125I]methyl-8-iodo-1, 3-dichlorodibenzofuran-Ah receptor complexes

J. Piskorska-Pliszczynska, B. Astroff, Timothy R. Zacharewski, +5

Archives of Biochemistry and Biophysics

Medicinal Chemistry3-Dichlorodibenzofuran-ah Receptor Complexes2,3,7,8-Tetrachlorodibenzo-p-dioxin AntagonistsBiochemistryMedicine +8

In situ and in vitro photoaffinity labeling of the nuclear aryl hydrocarbon receptor from transformed rodent and human cell lines

Xiaofang Wang, T.R. Narasimhan, V. Morrison, +1

Archives of Biochemistry and Biophysics

Signal TransductionMolecular PhysiologyPhotochemistryBiochemistryNatural Sciences +8