Spray-dried redispersible oil-in-water emulsion to improve oral bioavailability of poorly soluble drugs

Gilles Dollo, Pascal Le Corre, Alexis Guérin, +3

European Journal of Pharmaceutical Sciences

Oral BioavailabilitySoluble DrugsTopical DrugPharmaceutical TechnologyPharmacology +1

Specific and non-specific phagocytosis of ligand-grafted PLGA microspheres by macrophages

Nolwenn Brandhonneur, François Chevanne, Véronique Vié, +4

European Journal of Pharmaceutical Sciences

Macrophage BiologyInflammationGranulocyteImmunologyBiological Microenvironments +6

Alkalinization of Intracuff Lidocaine Improves Endotracheal Tube-Induced Emergence Phenomena

Jean‐Pierre Estèbe, Gilles Dollo, Pascal Le Corre, +4

Anesthesia & Analgesia

Group LbPlasma Lidocaine LevelsPatient SafetyIntracuff LidocaineEndotracheal Tube Cuff +9

Spray-dryed bupivacaine-loaded microspheres: in vitro evaluation and biopharmaceutics of bupivacaine following brachial plexus administration in sheep

Pascal Le Corre, Jean Pierre Estèbe, Rozenn Clément, +4

International Journal of Pharmaceutics

SurgeryBiomedical EngineeringSpray-dryed Bupivacaine-loaded MicrospheresAnesthesiaMedicine +5

Improvement in solubility and dissolution rate of 1,2‐dithiole‐3‐thiones upon complexation with β‐cyclodextrin and its hydroxypropyl and sulfobutyl ether‐7 derivatives

Gilles Dollo, Pascal Le Corre, Marylène Chollet, +4

Journal of Pharmaceutical Sciences

Inclusion complexation of amide-typed local anesthetics with β-cyclodextrin and its derivatives. III. Biopharmaceutics of bupivacaine-SBE7-βCD complex following percutaneous sciatic nerve administration in rabbits

Gilles Dollo, Diane Oenning Thompson, Pascal Le Corre, +2

International Journal of Pharmaceutics

Medicinal ChemistryAnesthesiaAmide-typed Local AnestheticsPain MedicineMedicine +10

Endotracheal tube cuffs filled with lidocaine as a drug delivery system: in vitro and in vivo investigations

Gilles Dollo, Jean-Pierre Estèbe, Pascal Le Corre, +3

European Journal of Pharmaceutical Sciences

Anesthesia PracticeVivo InvestigationsLocal Anesthetic PharmacologyBiomedical EngineeringEndotracheal Tube Cuffs +5

Biopharmaceutics and metabolism of yohimbine in humans

Pascal Le Corre, Gilles Dollo, François Chevanne, +1

European Journal of Pharmaceutical Sciences

Pharmacological StudyBiochemistryMedicinePharmacotherapyMetabolomics +2

Epidural, intrathecal and plasma pharmacokinetic study of epidural ropivacaine in PLGA-microspheres in sheep model

Maja Ratajczak-Enselme, Jean-Pierre Estèbe, Gilles Dollo, +5

European Journal of Pharmaceutics and Biopharmaceutics

Spinal Cord InjuryPlasma Pharmacokinetic StudyLocal Anesthetic PharmacologyPain ManagementSheep Model +6

Determination of yohimbine and its two hydroxylated metabolites in humans by high-performance liquid chromatography and mass spectral analysis

Roger Le Verge, Pascal Le Corre, François Chevanne, +3

Journal of Chromatography B Biomedical Sciences and Applications

Mass Spectral AnalysisBiochemistryGas ChromatographyMedicineBioanalysis +10