Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein

Michiari Okuda, Kui Li, Michael R. Beard, +4

Gastroenterology

InflammationHepatologyMitochondrial FunctionBiochemistryViral Hepatitis +12

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus

Hervé Lerat, Masao Honda, Michael R. Beard, +7

Gastroenterology

Hepatitis C Virus–Induced Reactive Oxygen Species Raise Hepatic Iron Level in Mice by Reducing Hepcidin Transcription

Sohji Nishina, Keisuke Hino, Masaaki Korenaga, +9

Gastroenterology

Hepcidin TranscriptionHepatic DisordersHepatologyIron MetabolismLiver Physiology +11

Hepatic Iron Overload Induces Hepatocellular Carcinoma in Transgenic Mice Expressing the Hepatitis C Virus Polyprotein

Takakazu Furutani, Keisuke Hino, Michiari Okuda, +9

Gastroenterology

Differences in Hypervariable Region 1 Quasispecies of Hepatitis C Virus in Human Serum, Peripheral Blood Mononuclear Cells, and Liver

Michiari Okuda, Keisuke Hino, Masaaki Korenaga, +3

Hepatology

Hepatitis C VirusImmunologyPathologyHvr 1Autoimmune Liver Disease +15

Glycine-to-arginine substitution at codon 145 of HBsAg in two infants Born to hepatitis B e antigen-positive carrier

Keisuke Hino, Michiari Okuda, Osamu Hashimoto, +5

Digestive Diseases and Sciences

VaccinationMaternal ImmunizationGlycine-to-arginine SubstitutionHepatologyCodon 145 +7

Hepatitis C virus core protein inhibits deoxycholic acid-mediated apoptosis despite generating mitochondrial reactive oxygen species

Yuichi Hara, Keisuke Hino, Michiari Okuda, +8

Journal of Gastroenterology

Deoxycholic Acid-mediated ApoptosisHepatologyBiochemistryMitochondrial FunctionViral Hepatitis +10

Extracellular release of peroxidase from eosinophils by interaction with immune complexes.

Toru Takenaka, Michiari Okuda, Shinichi Kawabori, +1

PubMed

AsthmaImmunologyMuch PeroxidaseAllergenRabbit Antibody +18

In situ detection of oxidized n-3 polyunsaturated fatty acids in chronic hepatitis C: correlation with hepatic steatosis

Akira Kitase, Keisuke Hino, Takakazu Furutani, +6

Journal of Gastroenterology

HepatologyBiochemistryFatty AcidsMedicineLiver Physiology +9

Stronger Neo‐Minophagen C^™, a glycyrrhizin‐containing preparation, protects liver against carbon tetrachloride‐induced oxidative stress in transgenic mice expressing the hepatitis C virus polyprotein

Isao Hidaka, Keisuke Hino, Masaaki Korenaga, +5

Liver International