Structure−Activity Relationships in a Series of Substituted Indolocarbazoles:  Topoisomerase I and Protein Kinase C Inhibition and Antitumoral and Antimicrobial Properties

Elisabète Rodrigues Pereira, Laure Belin, Martine Sancelme, +7

Journal of Medicinal Chemistry

In vitro uptake of technetium-99m-teboroxime in carcinoma cell lines and normal cells: comparison with technetium-99m-sestamibi and thallium-201.

Jean C. Maublant, Zheng Zhang, Maryse Rapp, +3

PubMed

Vitro UptakePathologyTumor BiologyOncologyRadiopharmaceutical Therapy +14

Synthesis and in Vitro Evaluation of Quaternary Ammonium Derivatives of Chlorambucil and Melphalan, Anticancer Drugs Designed for the Chemotherapy of Chondrosarcoma

Isabelle Giraud, Maryse Rapp, Jean‐Claude Maurizis, +1

Journal of Medicinal Chemistry

Anticancer Drugs DesignedMedicinal ChemistryPolymer-drug ConjugateMedicineBioconjugation +13

New Quaternary Ammonium Oxicam Derivatives Targeted toward Cartilage:  Synthesis, Pharmacokinetic Studies, and Antiinflammatory Potency

C. Nicolas, MICHEL VERNY, Isabelle Giraud, +4

Journal of Medicinal Chemistry

Pharmaceutical SciencePharmacotherapyPharmaceutical ChemistryOrthopaedic SurgeryMusculoskeletal Research +16

A methionine-free diet associated with nitrosourea treatment down-regulates methylguanine-DNA methyl transferase activity in patients with metastatic cancer.

Émilie Thivat, Xavier Durando, Aïcha Demidem, +7

PubMed

Application to a Cartilage Targeting Strategy:  Synthesis and in Vivo Biodistribution of ¹⁴C-Labeled Quaternary Ammonium−Glucosamine Conjugates

Isabelle Giraud, Maryse Rapp, Jean‐Claude Maurizis, +1

Bioconjugate Chemistry

Tissue EngineeringPharmaceutical ScienceEngineeringBiomedical EngineeringRadioactivity Level +16

Effects of Low-Dose Neutrons Applied at Reduced Dose Rate on Human Melanoma Cells

C Dionet, Andréï Tchirkov, Jean Pierre Alard, +11

Radiation Research

Antimicrobial Activities of Indolocarbazole and Bis-indole Protein Kinase C Inhibitors. II. Substitution on Maleimide Nitrogen with Functional Groups Bearing a Labile Hydrogen.

Elisabète Rodrigues Pereira, Serge Fabre, Martine Sancelme, +2

The Journal of Antibiotics

Protein kinase C inhibitors; Structure—activity relationships in K252c-related compounds

Serge Fabre, Michelle Prudhomme, Maryse Rapp

Bioorganic & Medicinal Chemistry

Molecular PharmacologyBiochemistryMedicineDrug DiscoveryRational Drug Design +2

Synthesis, Radiosynthesis, and Biological Evaluation of New Proteasome Inhibitors in a Tumor Targeting Approach

Magali Vivier, Maryse Rapp, Janine Papon, +4

Journal of Medicinal Chemistry

New Proteasome InhibitorsIodine AldehydeTumor BiologyMedicinal ChemistryOncology +15