J.H.T.M. Ploemen

Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate

J.H.T.M. Ploemen, Ben van Ommen, Peter J. van Bladeren · Biochemical Pharmacology · 1990 · 166 citations

Ethacrynic Acid, Biochemistry, Medicine +6

Reversible conjugation of ethacrynic acid with glutathione and human glutathione S-transferase P1-1.

J.H.T.M. Ploemen, Arne van Schanke, Ben van Ommen et al. · PubMed · 1994 · 84 citations

Pharmaceutical Science, Ethacrynic Acid, Biochemistry +12

Active site-directed irreversible inhibition of glutathione S-transferases by the glutathione conjugate of tetrachloro-1,4-benzoquinone.

Ben van Ommen, Cathaline den Besten, A.L.M. Rutten et al. · Journal of Biological Chemistry · 1988 · 80 citations · Full text

Molecular Pharmacology, Inhibitory Activity, Pharmaceutical Chemistry +13

Irreversible inhibition of rat glutathione <i>S</i>-transferase 1-1 by quinones and their glutathione conjugates. Structure-activity relationship and mechanism

Ben van Ommen, J.H.T.M. Ploemen, Jan J.P. Bogaards et al. · Biochemical Journal · 1991 · 67 citations · Full text

Molecular Pharmacology, Biochemistry, Irreversible Inhibition +12

Studies on the active site of rat glutathione <i>S</i>‐transferase isoenzyme 4–4

Ben van Ommen, J.H.T.M. Ploemen, Hendrik J.T. Ruven et al. · European Journal of Biochemistry · 1989 · 42 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Biochemistry +13