PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

Hiroshi Iwata, Claudia Goettsch, Amitabh Sharma, +16

Nature Communications

Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress

Maximillian A. Rogers, Natalia Maldonado, Joshua D. Hutcheson, +7

Circulation Research

Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization

Hideki Fujino, Iwao Yamada, Shunsuke Shimada, +2

Xenobiotica

Metabolomic ProfilingPitavastatin Lactone FormationPitavastatin LactoneBiosynthesisHmg-coa Reductase +17

Total Synthesis of Spicamycin

Tamotsu Suzuki, Sayaka Suzuki, Iwao Yamada, +3

The Journal of Organic Chemistry

Cystathionine γ-lyase Accelerates Osteoclast Differentiation

Takahiro Ito, Natalia Maldonado, Iwao Yamada, +5

Arteriosclerosis Thrombosis and Vascular Biology

Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reductase. (5). In Vitro Metabolism and Plasma Protein Binding in Animals and Human.

Hideki Fujino, Iwao Yamada, Junji Kojima, +3

Drug Metabolism and Pharmacokinetics

ImmunologyCellular PharmacologyMetabolic RemodelingMolecular PharmacologyNk-104 Bound +18

Metabolic Fate of Pitavastatin (NK-104), a New Inhibitor of 3-Hydroxy-3-methyllutaryl Coenzyme A Reductase

Hideki Fujino, Iwao Yamada, Syunsuke Shimada, +2

Arzneimittelforschung

Metabolic FatePitavastatin MetabolismMetabolomic ProfilingPharmacotherapyMetabolic Remodeling +16

Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans

Iwao Yamada, Hideki Fujino, Shunsuke Shimada, +1

Xenobiotica

Total Synthesis of Spicamycin Amino Nucleoside

Tamotsu Suzuki, Sayaka Tanaka, Iwao Yamada, +3

Organic Letters

Pd-Catalyzed coupling reaction of glycosylamines with 6-chloropurines: Synthesis of 6-(β-d-mannopyranosylamino)-9H-purine and its β-d-gluco isomer, N-glycoside models for spicamycin and septacidin

Noritaka Chida, Tamotsu Suzuki, Sayaka Tanaka, +1

Tetrahedron Letters

Medicinal ChemistryBiosynthesisBioorganic ChemistryEngineeringBiochemistry +8