A Nicotine Conjugate Vaccine Reduces Nicotine Distribution to Brain and Attenuates Its Behavioral and Cardiovascular Effects in Rats

Paul R. Pentel, David H. Malin, Sofiane Ennifar, +9

Pharmacology Biochemistry and Behavior

Tobacco ControlTobacco UseNeurophysiologyBehavioral NeuroscienceMedicine +8

Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain

Yoko Hieda, Daniel E. Keyler, Sofiane Ennifar, +2

International Journal of Immunopharmacology

VaccinationTobacco ControlNicotine DistributionContinued Nicotine AdministrationMedicine +5

Active Immunization Alters the Plasma Nicotine Concentration in Rats

Yoko Hieda, Daniel E. Keyler, J T Vandevoort, +4

Journal of Pharmacology and Experimental Therapeutics

Immunization of rats reduces nicotine distribution to brain

Yoko Hieda, Dan E. Keyler, John T. VanDeVoort, +4

Psychopharmacology

Tobacco ControlNeurophysiologyMedicineNicotineNeuropharmacology +6

High-level secretion of two antibody single chain Fv fragments by Pichia pastoris

Patrick Eldin, Mary E. Pauza, Yoko Hieda, +4

Journal of Immunological Methods

Protein SecretionNatural SciencesPathogenesisMolecular BiologyVirology +6

Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats

Mark LeSage, Daniel E. Keyler, Yoko Hieda, +4

Psychopharmacology

Tobacco CessationVaccinationTobacco ControlNicotine Self-administrationTobacco Use +7

Altered disposition of repeated nicotine doses in rats immunized against nicotine

Daniel E. Keyler, Yoko Hieda, John V. St. Peter, +1

Nicotine & Tobacco Research

Passive immunization against nicotine prevents nicotine alleviation of nicotine abstinence syndrome

David H. Malin, John R. Lake, Andy Lin, +7

Pharmacology Biochemistry and Behavior

VaccinationTobacco ControlTobacco UseNicotinePassive Immunization +6

Simple Extractive Derivatization of Methamphetamine and its Metabolites in Biological Materials with Extrelut® Columns for their GC-MS Determination*

Kenji Hara, S. Kashimura, Yoko Hieda, +1

Journal of Analytical Toxicology

EngineeringExtrelut ColumnForensic ChemistryBiological MaterialsPorcine Skeletal Muscle +20

Distribution and disposition of benzalkonium chloride following various routes of administration in rats

Yuying Xue, Yoko Hieda, Yoji Saito, +5

Toxicology Letters

Pharmacological StudyMedicinePhysiologyBenzalkonium ChlorideToxicology +5