The Noncoding RNA <i>MALAT1</i> Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Tony Gutschner, Monika Hämmerle, Jeff Hsu, +10

Cancer Research

Human blood vessel organoids as a model of diabetic vasculopathy

Reiner Wimmer, Alexandra Leopoldi, Martin Aichinger, +17

Nature

Vascular DiseaseCardiovascular DiseaseVascular AdaptationPhysiologyDiabetes +6

Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

Luca Quagliata, Matthias S. Matter, Salvatore Piscuoglio, +14

Hepatology

Loss of the abundant nuclear non-coding RNA<i>MALAT1</i>is compatible with life and development

Tony Gutschner, Monika Hämmerle, Stefan Günther, +7

RNA Biology

GeneticsLung AdenocarcinomaRna SplicingMolecular GeneticsKnockout Mouse Model +19

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)

Monika Hämmerle, Tony Gutschner, Hannah J. Uckelmann, +9

Hepatology

Insulin-Like Growth Factor 2 mRNA-Binding Protein 1 (IGF2BP1) Is an Important Protumorigenic Factor in Hepatocellular Carcinoma

Tony Gutschner, Monika Hämmerle, Nikolaos Pazaitis, +14

Hepatology

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

Dontscho Kerjaschki, Zsuzsanna Bagó-Horváth, Margaretha Rudas, +34

Journal of Clinical Investigation

Circular DefectsBreast OncologyAngiogenesisDistant Organ MetastasisMedicine +13

NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

Caroline Vonach, Katharina Viola, Benedikt Giessrigl, +23

British Journal of Cancer

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

Sven Hagemann, Danny Misiak, Jessica L. Bell, +8

Molecular Cancer

Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer

Tom Kaune, Heidi Griesmann, Katharina Theuerkorn, +10

iScience