Ursolic acid reduces hepatocellular apoptosis and alleviates alcohol-induced liver injury via irreversible inhibition of CASP3 in vivo

Xiaoyao Ma, Man Zhang, Fang Ge, +7

Acta Pharmacologica Sinica

Alcohol-induced Liver InjuryHepatologyBiochemistryIrreversible InhibitionMedicine +11

Unusual origins of the buccal and mylohyoid nerves

Nina G. Jablonski, Chuanjing Cheng, Lim-Keak Cheng, +1

Oral Surgery Oral Medicine Oral Pathology

BiologyNeuroanatomyUnusual OriginsPeripheral NerveAnatomy +6

Comprehensive TCM molecular networking based on MS/MS in silico spectra with integration of virtual screening and affinity MS screening for discovering functional ligands from natural herbs

Zhihua Wang, Unchol Kim, Jin‐Biao Liu, +7

Analytical and Bioanalytical Chemistry

Molecular DockingMolecular RecognitionMedicinal ChemistryBiochemistryMedicine +11

Resveratrol targeting NRF2 disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage in mice pulmonary infection

Fuyun Chi, Chuanjing Cheng, Man Zhang, +3

Journal of Ethnopharmacology

InflammationNrf2-dlg MotifReductive StressOxidative Stress DamageMedicine +9

Cinnamaldehyde Enhances Antimelanoma Activity through Covalently Binding ENO1 and Exhibits a Promoting Effect with Dacarbazine

Weiyi Zhang, Jie Gao, Chuanjing Cheng, +8

Cancers

Ginsenoside CK targeting KEAP1-DGR/Kelch domain disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage

Chuanjing Cheng, Jinling Zhang, Kaixin Liu, +6

Phytomedicine

InflammationReductive StressSignal TransductionKeap1-dgr/kelch DomainOxidative Stress Damage +13

Apoptosis effect of Aegiceras corniculatum on human colorectal cancer via activation of FoxO signaling pathway

Hua Luo, Erwei Hao, Dechao Tan, +12

Food and Chemical Toxicology

Aegiceras CorniculatumChemoprevention StrategyOncogenic AgentApoptosisColorectal Cancer +9

Baicalein disrupts the KEAP1-NRF2 interaction to alleviate oxidative stress injury by inhibiting M1 macrophage polarization

Fuyun Chi, Chuanjing Cheng, Kaixin Liu, +4

Free Radical Biology and Medicine

Lepidiline A Improves the Balance of Endogenous Sex Hormones and Increases Fecundity by Targeting HSD17B1

Chuanjing Cheng, Fukui Shen, Guoyu Ding, +8

Molecular Nutrition & Food Research

The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism

Fang Ge, Chuanjing Cheng, Manqian Zhang, +6

Journal of Functional Foods