PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus

Gerolama Condorelli, Giovanni Vigliottá, Carlo Iavarone, +8

The EMBO Journal

Metabolic SyndromeGeneticsPhysiologyDiabetesType 2 +6

Evidence That IRS-2 Phosphorylation Is Required for Insulin Action in Hepatocytes

Kristina I. Rother, Yumi Imai, Matilde Caruso, +3

Journal of Biological Chemistry

Insulin ReceptorsIrs-2 PhosphorylationInsulin SignalingMetabolic SyndromeReceptor Tyrosine Kinase +20

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

Gerolama Condorelli, Giovanni Vigliottá, Almerinda Cafieri, +7

Oncogene

Signaling PathwayFas/tnfr1-induced ApoptosisApoptosisCell DeathTumor Suppressor +3

Targeted gene transfer in eucaryotic cells by dye-assisted laser optoporation

Giuseppe Palumbo, Matilde Caruso, Elvira Crescenzi, +3

Journal of Photochemistry and Photobiology B Biology

MedicineMolecular BiologyGene DeliveryGene VectorCell Manipulation +3

Activation and Mitochondrial Translocation of Protein Kinase Cδ Are Necessary for Insulin Stimulation of Pyruvate Dehydrogenase Complex Activity in Muscle and Liver Cells

Matilde Caruso, Maria Alessandra Maitan, Giuseppe Bifulco, +5

Journal of Biological Chemistry

Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells

Gerolama Condorelli, Giovanni Vigliottá, Alessandra Trencia, +7

Diabetes

Insulin-Activated Protein Kinase Cβ Bypasses Ras and Stimulates Mitogen-Activated Protein Kinase Activity and Cell Proliferation in Muscle Cells

Pietro Formisano, Francesco Oriente, Francesca Fiory, +7

Molecular and Cellular Biology

Cell ProliferationCellular PhysiologyInsulin SignalingMolecular PharmacologySignaling Pathway +17

In NIH-3T3 Fibroblasts, Insulin Receptor Interaction with Specific Protein Kinase C Isoforms Controls Receptor Intracellular Routing

Pietro Formisano, Francesco Oriente, Claudia Miele, +5

Journal of Biological Chemistry

Insulin SignalingSignal TransductionSignaling PathwayBiochemistryG Protein-coupled Receptor +8

Differential Role of Insulin Receptor Substrate (IRS)-1 and IRS-2 in L6 Skeletal Muscle Cells Expressing the Arg1152 → Gln Insulin Receptor

Claudia Miele, Matilde Caruso, Véronique Calleja, +8

Journal of Biological Chemistry

Insulin Receptor Substrate-2 Phosphorylation Is Necessary for Protein Kinase Cζ Activation by Insulin in L6hIR Cells

Francesco Oriente, Pietro Formisano, Claudia Miele, +8

Journal of Biological Chemistry

Insulin Receptor BindingInsulin ReceptorCellular PhysiologyInsulin SignalingMetabolic Syndrome +16