Quercetin Enhances Melanogenesis By Increasing the Activity and Synthesis of Tyrosinase in Human Melanoma Cells and in Normal Human Melanocytes

Hidetaka Nagata, Susumu Takekoshi, Reiko Takeyama, +2

Pigment Cell Research

<i>In situ</i> expression of corticotropin‐releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skin

Minori Kono, Hidetaka Nagata, Sinobu Umemura, +2

The FASEB Journal

Expression and localization of leptin receptor in the normal rat pituitary gland

Masayuki Sone, Hidetaka Nagata, Susumu Takekoshi, +1

Cell and Tissue Research

Developmental BiologySignal TransductionPituitary GlandHormonal ReceptorPhysiology +8

Neuronal brain‐derived neurotrophic factor manipulates microglial dynamics

Junya Onodera, Hidetaka Nagata, Ai Nakashima, +2

Glia

Flavonoids enhance melanogenesis in human melanoma cells.

Susumu Takekoshi, Hidetaka Nagata, Kanae Kitatani

PubMed

BiochemistryMore FlavonoidsMedicineMelanomaHuman Malignant Melanoma +8

Quercetin-Induced Melanogenesis in a Reconstituted Three-Dimensional Human Epidermal Model

Reiko Takeyama, Susumu Takekoshi, Hidetaka Nagata, +2

Journal of Molecular Histology

Cutaneous BiologyWound HealingDermatologyMatrix BiologyQuercetin-induced Melanogenesis +4

Synthesis and SAR study of imidazoquinolines as a novel structural class of microsomal prostaglandin E2 synthase-1 inhibitors

Tomoya Shiro, Hirotada Takahashi, Keisuke Kakiguchi, +4

Bioorganic & Medicinal Chemistry Letters

Combinatorial ChemistryNovel Structural ClassMedicinal ChemistryBiochemistryNatural Sciences +7

7-Phenyl-imidazoquinolin-4(5H)-one derivatives as selective and orally available mPGES-1 inhibitors

Tomoya Shiro, Keisuke Kakiguchi, Hirotada Takahashi, +2

Bioorganic & Medicinal Chemistry

Medicinal ChemistryMedicinePharmacological AgentPharmacotherapyDrug Development +4

A novel and potent biological antioxidant, Kinobeon A, from cell culture of safflower

Tsutomu Kanehira, Susumu Takekoshi, Hidetaka Nagata, +4

Life Sciences

Food ChemistryPolyphenolicsEngineeringBiochemistryPotent Biological Antioxidant +7

Synthesis and biological evaluation of substituted imidazoquinoline derivatives as mPGES-1 inhibitors

Tomoya Shiro, Keisuke Kakiguchi, Hirotada Takahashi, +2

Bioorganic & Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)BiochemistryAntiparasitic AgentSubstituted Imidazoquinoline Derivatives +10