Functional analysis of secreted and transmembrane proteins critical to mouse development

Kevin J. Mitchell, Kathy Pinson, Olivia Kelly, +13

Nature Genetics

Protein SecretionProtein FunctionSignal TransductionDevelopmental BiologyTransmembrane Proteins +9

DNA Methylation Specifies Chromosomal Localization of MeCP2

Xinsheng Nan, Peri Tate, En Li, +1

Molecular and Cellular Biology

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyMolecular Genetics +14

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a

Xiaolin Gao, Peri Tate, Ping Hu, +3

Proceedings of the National Academy of Sciences

Es Cell PluripotencyGeneticsGenomic MechanismBaf250a-mediated ChromatinEpigenetics +17

The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse

Peri Tate, William Skarnes, Adrian Bird

Nature Genetics

Developmental BiologyDevelopmental GeneticsCraniofacial DevelopmentEmbryonic DevelopmentCell Fate Determination +5

Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9

Jinxiong Han, Jun Zhang, Li Chen, +6

RNA Biology

EngineeringIn Vivo Gene TherapyGeneticsMolecular BiologyVivo Deletion +15

Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse

Paula A. Coelho, Leah Bury, Marta N. Shahbazi, +9

Open Biology

PathologyCell ProliferationCancer BiologyCellular PhysiologyTumor Biology +19

Capturing novel mouse genes encoding chromosomal and other nuclear proteins

Peri Tate, Muriel Lee, Susan Tweedie, +2

Journal of Cell Science

GeneticsGenomic MechanismMolecular GeneticsSplicing VariantTranscriptional Regulation +14

Characterization of Two Distinct Nucleosome Remodeling and Deacetylase (NuRD) Complex Assemblies in Embryonic Stem Cells

Daniel Bode, Lu Yu, Peri Tate, +2

Molecular & Cellular Proteomics

Nurd ComplexMolecular BiologyNurd FunctionCell SpecializationEpigenetics +21

An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers

Cynthia L. Fisher, Hendrik Marks, Lily Ting-yin Cho, +9

Nucleic Acids Research

EngineeringEfficient MethodEpigenetic ChangeGeneticsEpigenetics +19

Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis

Ioannis Kasioulis, Heather M. Syred, Peri Tate, +10

Molecular Biology of the Cell

SpermatogenesisEpigenetic ChangeGeneticsMolecular BiologyLysine Demethylation Activity +27