Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice

Chen-Ching Yuan, Priya Muthu, Katarzyna Kaźmierczak, +6

Proceedings of the National Academy of Sciences

Cardiac MuscleHcm MiceHcm-rlc MiceCellular PhysiologyCell Signaling +14

The effect of myosin RLC phosphorylation in normal and cardiomyopathic mouse hearts

Priya Muthu, Katarzyna Kaźmierczak, Michelle Jones, +1

Journal of Cellular and Molecular Medicine

Muscle FibresCardiac MuscleCardiomyopathyHeart FailureMolecular Physiology +13

Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction

Priya Muthu, Li Wang, Chen‐Ching Yuan, +6

The FASEB Journal

Discrete effects of A57G-myosin essential light chain mutation associated with familial hypertrophic cardiomyopathy

Katarzyna Kaźmierczak, Ellena C. Paulino, Wenrui Huang, +6

American Journal of Physiology-Heart and Circulatory Physiology

Cardiac MuscleHeart FailureHuman Cardiac ElcFamilial Hypertrophic CardiomyopathyGenetics +21

Myosin regulatory light chain mutation found in hypertrophic cardiomyopathy patients increases isometric force production in transgenic mice

Katarzyna Kaźmierczak, Priya Muthu, Wenrui Huang, +3

Biochemical Journal

Cardiac MuscleHeart FailureGeneticsCytoskeletonTransgenic Mice +16

In vitro rescue study of a malignant familial hypertrophic cardiomyopathy phenotype by pseudo-phosphorylation of myosin regulatory light chain

Priya Muthu, Jingsheng Liang, William M. Schmidt, +2

Archives of Biochemistry and Biophysics

Cardiac MuscleCardiomyopathyHeart FailurePathologyVitro Rescue Study +3

Characterizations of myosin essential light chain’s N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to sinusoidal length alterations

Li Wang, Priya Muthu, Danuta Szczesna‐Cordary, +1

Journal of Muscle Research and Cell Motility

Muscle FunctionMolecular BiologyCytoskeletonMechanotransductionCellular Physiology +15

Rotation of actin monomers during isometric contraction of skeletal muscle

Julian Borejdo, Priya Muthu, John M. Talent, +2

Journal of Biomedical Optics

Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice

Wenrui Huang, Jingsheng Liang, Katarzyna Kaźmierczak, +9

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyMolecular PhysiologyGenetic DisorderMedicine +7

Single molecule kinetics in the familial hypertrophic cardiomyopathy D166V mutant mouse heart

Priya Muthu, Prasad Mettikolla, Nils Calander, +5

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyHeart FailureMolecular PhysiologyBiochemistry +7