BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation

L Cabon, Patricia Galán‐Malo, Aïda Bouharrour, +5

Cell Death and Differentiation

InflammationAutoimmune DiseaseApoptosisCell DeathBax Activation +4

AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation

Mathieu Baritaud, L Cabon, Laure Delavallée, +4

Cell Death and Disease

TNFα kinoid vaccination-induced neutralizing antibodies to TNFα protect mice from autologous TNFα-driven chronic and acute inflammation

Hélène Le Buanec, Laure Delavallée, Natacha Bessis, +5

Proceedings of the National Academy of Sciences

ImmunologyImmune RegulationPathologyImmunologic MechanismImmune System +19

Interplay between TNF and Regulatory T Cells in a TNF-Driven Murine Model of Arthritis

Jérôme Biton, Luca Semerano, Laure Delavallée, +5

The Journal of Immunology

T-regulatory CellImmunologyImmune RegulationRegulatory T CellsCd4 T Cell Responses +21

In Vivo Expansion of Activated Foxp3+ Regulatory T Cells and Establishment of a Type 2 Immune Response upon IL-33 Treatment Protect against Experimental Arthritis

Jérôme Biton, Allan Thiolat, François Santinon, +10

The Journal of Immunology

AIF loss deregulates hematopoiesis and reveals different adaptive metabolic responses in bone marrow cells and thymocytes

Lauriane Cabon, Audrey Bertaux, Marie-Noëlle Brunelle-Navas, +15

Cell Death and Differentiation

InflammationLymphocyte DevelopmentImmunologyHematologyCell Death +7

Active immunization against IL-23p19 improves experimental arthritis

Rojo A. Ratsimandresy, Emilie Duvallet, Éric Assier, +5

Vaccine

Rheumatoid DisorderRheumatologyAutoimmune DiseaseImmunologyAutoimmunity +6

Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus

Laure Delavallée, Navrita Mathiah, Lauriane Cabon, +17

Molecular Metabolism

Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis

Laure Delavallée, Luca Semerano, Éric Assier, +6

Arthritis Research & Therapy

Kinoid of human tumor necrosis factor-alpha for rheumatoid arthritis

Luca Semerano, Éric Assier, Laure Delavallée, +1

Expert Opinion on Biological Therapy

ImmunologyImmune RegulationPathologyBiological TherapyImmunotherapeutics +19