Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes

J. Kim, Min Xu, R. Xo, +4

Osteoarthritis and Cartilage

InflammationDna DamageMitochondrial FunctionPro-inflammatory CytokinesMitochondrial Dna Damage +10

Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells.

Wesley J. Driggers, Susan P. LeDoux, G. L. Wilson

Journal of Biological Chemistry

Dna DamageLipid PeroxidationOxidative DamageMolecular BiologySugar Lesions +14

Nuclear Import of Plasmid DNA in Digitonin-permeabilized Cells Requires Both Cytoplasmic Factors and Specific DNA Sequences

G. L. Wilson, Brenda S. Dean, Gan Wang, +1

Journal of Biological Chemistry

Repair of alkali-labile sites within the mitochondrial DNA of RINr 38 cells after exposure to the nitrosourea streptozotocin.

Cathy Pettepher, Susan P. LeDoux, Vilhelm A. Bohr, +1

Journal of Biological Chemistry

Genome InstabilityDna DamageMitochondrial FunctionBiochemistryNatural Sciences +13

Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes

Valentina Grishko, R. Ho, G. L. Wilson, +1

Osteoarthritis and Cartilage

Mitochondrial Dna IntegrityMitochondrial FunctionGeneticsCartilage DegenerationOsteoarthritis +6

Palmitate Induced Mitochondrial Deoxyribonucleic Acid Damage and Apoptosis in L6 Rat Skeletal Muscle Cells

Lyudmila I. Rachek, S. I. Musiyenko, Susan P. LeDoux, +1

Endocrinology

MitophagyFatty Acid PalmitateLipid PeroxidationApoptosisCell Death +17

Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells

G. L. Wilson, Nancy J. Patton, Joe M. McCord, +2

Diabetologia

InflammationMedicineLipid PeroxidationImmunologyCell Death +8

Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes

Mikhail Alexeyev, N. I. Venediktova, Viktor Pastukh, +3

Gene Therapy

Mitochondrial MyopathyMitophagyMitochondrial BiogenesisMitochondrial FunctionGenetic Disorder +10

Mechanisms of Nitrosourea-Induced β-Cell Damage: Alterations in DNA

Susan P. LeDoux, S.E. Woodley, Nancy J. Patton, +1

Diabetes

Non-insulin-dependent diabetes-induced defects in cardiac cellular calcium regulation

S. Allo, Thomas Lincoln, G. L. Wilson, +3

American Journal of Physiology-Cell Physiology

Cardiac MuscleHeart FailureCardiovascular FunctionCellular PhysiologyInsulin Signaling +15