H. J. Kolker

Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line

Jun Ma, Marc Maliepaard, Kees Nooter et al. · British Journal of Cancer · 1998 · 62 citations

Cellular Accumulation, Novel Mechanism, Medicine +7

Pharmacokinetic-dynamic relationship of cisplatin in vitro: simulation of an i.v. bolus and 3 h and 20 h infusion

Jun Ma, Jaap Verweij, H. J. Kolker et al. · British Journal of Cancer · 1994 · 34 citations · Full text

Oncology, Physiologically-based Pharmacokinetic Modeling, Medicine +6

Species- and sex-related differences in the plasma clearance and metabolite formation of antipyrine. A comparative study in four animal species: Cattle, goat, rat and rabbit

Renger F. Witkamp, J.A.C.M. Lohuis, Sandra M. Nijmeijer et al. · Xenobiotica · 1991 · 28 citations

Hormonal regulation of oxidative drug metabolism in the dwarf goat. The effect of sex and hormonal treatment on plasma disposition and metabolite formation of sulphadimidine

Renger F. Witkamp, Gerben A.E. van 't Klooster, Sandra M. Nijmeijer et al. · Journal of Veterinary Pharmacology and Therapeutics · 1993 · 12 citations