Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

Michiko Mandai, Akira Watanabe, Yasuo Kurimoto, +35

New England Journal of Medicine

Ocular DiseaseBiomedical EngineeringStem Cell BiologyRegenerative MedicineRetina +15

Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification.

Je‐Tae Woo, Chikara Shinohara, Kaoru Sakai, +2

The Journal of Antibiotics

Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774

Je‐Tae Woo, Chikara Shinohara, Kaoru Sakai, +2

European Journal of Biochemistry

Staplabin, a Novel Fungal Triprenyl Phenol which Stimulates the Binding of Plasminogen to Fibrin and U937 Cell.

Chikara Shinohara, Keiji Hasumi, WATARU HATSUMI, +1

The Journal of Antibiotics

Inhibition of the uptake of oxidized low‐density lipoprotein in macrophage J774 by the antibiotic ikarugamycin

Keiji Hasumi, Chikara Shinohara, Shin Naganuma, +1

European Journal of Biochemistry

Lipid PeroxidationAntimicrobial ChemotherapyAntibiotic IkarugamycinOxidized Low‐density LipoproteinOxidative Stress +15

Enhancement of Fibrinolytic Activity of Vascular Endothelial Cells by Chaetoglobosin A, Crinipellin B, Geodin and Triticone B.

Chikara Shinohara, Toshihiro Chikanishi, SHIGEMITSU NAKASHIMA, +4

The Journal of Antibiotics

Gypsetin, a new inhibitor of acyl-CoA: cholesterol acyltransferase produced by Nannizzia gypsea var. incurvata IFO 9228. I. Fermentation, isolation, physico-chemical properties and biological activity.

Chikara Shinohara, Keiji Hasumi, Yoshio Takei, +1

The Journal of Antibiotics

Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

Kiyotake Suenaga, Susumu Kokubo, Chikara Shinohara, +2

Tetrahedron Letters

Novel Growth InhibitorsMedicineAnti-cancer AgentAmamistatins APharmacology +4

Enhancement of fibrin binding and activation of plasminogen by staplabin through induction of a conformational change in plasminogen

Ritsuko Takayasu, Keiji Hasumi, Chikara Shinohara, +1

FEBS Letters

Structures of Amamistatins A and B, Novel Growth Inhibitors of Human Tumor Cell Lines from Nocardia asteroides

Susumu Kokubo, Kiyotake Suenaga, Chikara Shinohara, +2

Tetrahedron

Novel Growth InhibitorsMedicineCancer GrowthAnti-cancer AgentAmamistatins A +5