Discovery and development of the anticancer agent salinosporamide A (NPI-0052)

William Fenical, Paul R. Jensen, Michael A. Palladino, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceOncologyChemoprevention StrategyAnticancer Agent +8

Structure−Activity Relationship Studies of Salinosporamide A (NPI-0052), a Novel Marine Derived Proteasome Inhibitor

Venkat R. Macherla, Scott S. Mitchell, Rama Rao Manam, +11

Journal of Medicinal Chemistry

Proteasome InhibitionMedicinal ChemistryPharmaceutical ChemistryBiochemistrySalinosporamide A +12

Lynamicins A−E, Chlorinated Bisindole Pyrrole Antibiotics from a Novel Marine Actinomycete

Katherine McArthur, Scott S. Mitchell, Ginger Tsueng, +5

Journal of Natural Products

Lajollamycin, a Nitro-tetraene Spiro-β-lactone-γ-lactam Antibiotic from the Marine Actinomycete <i>Streptomyces </i><i>n</i><i>odosus</i>

Rama Rao Manam, Sy Teisan, Donald J White, +7

Journal of Natural Products

Bioorganic ChemistryScripps CanyonAntimicrobial ChemotherapyDrug ResistanceEnvironmental Microbiology +14

Glaciapyrroles A, B, and C, Pyrrolosesquiterpenes from a <i>Streptomyces</i> sp. Isolated from an Alaskan Marine Sediment

Venkat R. Macherla, Jehnan Liu, Christopher Bellows, +4

Journal of Natural Products

BiosynthesisBioorganic ChemistryEngineeringBiochemistryBiochemical Taxonomy +11

Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp. I. Taxonomy, Fermentation and Biological Activities.

Wenying Li, John E. Leet, HELEN A. AX, +8

The Journal of Antibiotics

Aureoverticillactam, a Novel 22-Atom Macrocyclic Lactam from the Marine Actinomycete <i>Streptomyces aureoverticillatus</i>

Scott S. Mitchell, Benjamin Nicholson, Sy Teisan, +2

Journal of Natural Products

Novel AnticancerMedicinal ChemistryAntimicrobial Drug DiscoveryBioorganic ChemistryMarine Biotechnology +13

Lipoxazolidinones A, B, and C: Antibacterial 4-Oxazolidinones from a Marine Actinomycete Isolated from a Guam Marine Sediment

Venkat R. Macherla, Jehnan Liu, Michelle J. Sunga, +5

Journal of Natural Products

Antibacterial ActivityAntimicrobial ChemotherapyGuam Marine SedimentDrug ResistanceMicrobial Ecology +14

Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp. II. Isolation, Characterization, and Structure Determination.

John E. Leet, Wenying Li, HELEN A. AX, +7

The Journal of Antibiotics

Salinosporamides D−J from the Marine Actinomycete <i>Salinispora tropica</i>, Bromosalinosporamide, and Thioester Derivatives Are Potent Inhibitors of the 20S Proteasome

Katherine A. Reed, Rama Rao Manam, Scott S. Mitchell, +7

Journal of Natural Products

Salinosporamides FMedicinal ChemistryMarine BiotechnologyBiosynthesisPharmaceutical Science +13