Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.

Masami Suganuma, Hirota Fujiki, Hiroko Suguri, +7

Proceedings of the National Academy of Sciences

Black SpongeOkadaic AcidMedicineCutaneous BiologyPharmacology +11

Anticentromere Antibody as a Risk Factor for Cancer in Patients with Systemic Sclerosis

Maria de Lourdes Higuchi, Takahiko Horiuchi, Nagisa Ishibashi, +3

Clinical Rheumatology

Autoimmune DiseaseSystemic SclerodermaImmunologyPathologySystemic Sclerosis +4

A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: immunological analysis of B cells, T cells and cytokines

Yasuhiro Tamimoto, Takahiko Horiuchi, Hiroshi Tsukamoto, +12

Lara D. Veeken

Clinical ImmunologyImmunohematologyImmunodeficienciesImmunologyImmune Regulation +23

Mechanisms of action of okadaic acid class tumor promoters on mouse skin.

Hirota Fujiki, Masami Suganuma, S Yoshizawa, +3

Environmental Health Perspectives

PathologyDermatologyTumor BiologyReceptor Tyrosine KinaseCancer Cell Biology +18

Tumor-promoting activity of staurosporine, a protein kinase inhibitor on mouse skin.

S Yoshizawa, H Fujiki, Hiroko Suguri, +4

PubMed

DermatologyImmunotherapyTumor BiologyProtein Kinase InhibitorStaurosporine Alone +17

Specific mechanistic aspects of animal tumor promoters: the okadaic acid pathway.

Hirota Fujiki, Masami Suganuma, Shinji Nishiwaki, +7

PubMed

Transcriptional RegulationSignal TransductionSignaling PathwayMedicineGene Expression +10

Aberrant HS1 molecule in a patient with systemic lupus erythematosus

Takuya Sawabe, Takahiko Horiuchi, Ritsuko Koga, +9

Genes and Immunity

Aberrant Hs1 MoleculeAutoimmune DiseaseSystemic Lupus ErythematosusSystemic Lupus Erythematosus TreatmentLupus +6

Similar, potent tumor-promoting activity of all isomers of teleocidins A and B in a two-stage carcinogenesis experiment on the skin of CD-1 mice.

Hiroshi Fujiki, Masami Suganuma, M Ninomiya, +7

PubMed

Teleocidin B IsomersMolecular WeightsCancer BiologyCd-1 MiceTumor Biology +15

Chemistry and anti-tumor promoting activity of Morus flavonoids.

Tsuyoshi Nomura, Toshio Fukai, Y. Hano, +3

PubMed

Medicinal ChemistryMedicinePhytochemicalPharmacologyDrug Discovery +1

A new pathway of tumor promotion by the okadaic acid class compounds.

Hirota Fujiki, Masami Suganuma, Shinji Nishiwaki, +4

PubMed

Tumor BiologyChemoprevention StrategyBiochemistryMedicineCancer Biology +5