Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease

Hyundong Song, Minho Moon, Han Kyoung Choe, +6

Molecular Neurodegeneration

O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment

Chaeyoung Kim, Dong Woo Nam, Sangyoon Park, +9

Neurobiology of Aging

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineDegenerative PathologyProtein Misfolding +6

Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions

Sung Min Son, Hyundong Song, Jayoung Byun, +4

Autophagy

MitophagyInsulin-resistant ConditionsNeurochemical BiomarkersAutophagosomes ContributesType Ii +21

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

Eun Sun Jung, Hyunjung Choi, Hyundong Song, +4

Scientific Reports

Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease

Moon-Yong Cha, Yoo‐Wook Kwon, Hyo–Suk Ahn, +10

Stem Cells Translational Medicine

Altered APP Processing in Insulin-Resistant Conditions Is Mediated by Autophagosome Accumulation via the Inhibition of Mammalian Target of Rapamycin Pathway

Sung Min Son, Hyundong Song, Jayoung Byun, +4

Diabetes

MitophagyMouse BrainsNeurochemical BiomarkersAmyloid Precursor ProteinInsulin Signaling +24

Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer's Disease

Minho Moon, Hyun-Seok Hong, Dong Woo Nam, +6

Journal of Alzheimer s Disease

Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease

Tae‐Hun Kim, Ha Yun Yang, Beoung Gun Park, +12

European Journal of Medicinal Chemistry

Combinatorial ChemistryAlzheimer's DiseaseBiochemistryMitochondrial FunctionBenzimidazole Derivatives +9

Structure–activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template

Phuong‐Thao Tran, Van-Hai Hoang, Shivaji A. Thorat, +7

Bioorganic & Medicinal Chemistry

Structure–activity RelationshipMolecular PharmacologyBiochemistryMedicineNatural Sciences +10

Amyloid β‐induced elevation of O‐GlcNAcylated c‐Fos promotes neuronal cell death

Hee-Sun Choi, Chaeyoung Kim, Hyundong Song, +5

Aging Cell