Hemoglobin debrousse (β96[FG3]Leu → Pro): A new unstable hemoglobin with twofold increased oxygen affinity

Philippe Lacan, J. Kister, Alain Francina, +4

American Journal of Hematology

Iron MetabolismImmunologyMolecular BiologyPathologyOxygen Affinity +17

Detection of a Thalassemic α-Chain Variant (Hemoglobin Groene Hart) by Reversed-Phase Liquid Chromatography

Isabelle Zanella‐Cléon, Michel Becchi, Philippe Lacan, +3

Clinical Chemistry

Rapid and reliable β-globin gene cluster haplotyping of sickle cell disease patients by FRET Light Cycler and HRM assays

Philippe Joly, Philippe Lacan, Caroline Garcia, +2

Clinica Chimica Acta

ImmunohematologyFret Light CyclerLaboratory HematologyHealth SciencesMedicine +6

Identification and molecular characterization of four new large deletions in the β-globin gene cluster

Philippe Joly, Philippe Lacan, Caroline Garcia, +2

Blood Cells Molecules and Diseases

Molecular CharacterizationGeneticsMolecular BiologyMolecular GeneticsDisease Gene Identification +5

Rapid genotyping of two common G6PD variants, African (A-) and Mediterranean, by high-resolution melting analysis

Philippe Joly, Philippe Lacan, Caroline Garcia, +2

Clinical Biochemistry

BiologyCommon G6pd VariantsNatural SciencesGeneticsMolecular Biology +6

Genetic Background of the Sickle Cell Disease Pediatric Population of Dakar, Senegal, and Characterization of a Novel Frameshift <b>β</b>-Thalassemia Mutation [<i>HBB</i>: c.265_266del; p.Leu89Glufs*2]

Fatou Guèye Tall, Cyril Martin, El Hadji Malick Ndour, +13

Hemoglobin

Identification by Mass Spectrometry of a Hemoglobin Variant with an Elongated β-Globin Chain

Philippe Lacan, Michel Becchi, Isabelle Zanella‐Cléon, +4

Clinical Chemistry

ImmunohematologyHbvar DatabaseGeneticsBiological Mass SpectrometryMolecular Biology +23

THROMBOTIC EVENTS IN COMPOUND HETEROZYGOTES FOR A HIGH AFFINITY HEMOGLOBIN VARIANT: Hb MILLEDGEVILLE [<b>α</b>44(CE2)Pro→Leu (<b>α</b>2)] AND FACTOR V LEIDEN

Michel Hanss, Philippe Lacan, Martine Aubry, +2

Hemoglobin

ImmunohematologyGeneticsGenetic EpidemiologyImmunologyPathology +14

Two New α Chain Variants: Hb Die [α93(FG5)Val→Ala (α1)] and Hb Beziers [α99(G6)Lys→Asn (α1)]

Philippe Lacan, Martine Aubry, Nicole Couprie, +1

Hemoglobin

GeneticsHematologyPathologyMolecular GeneticsSpina Bifida +1

Characterization of three new deletions in the β-globin gene cluster during a screening survey in two French urban areas

Serge Pissard, Valérie Raclin, Philippe Lacan, +4

Clinica Chimica Acta

GeneticsGenetic EpidemiologyBiostatisticsGenomicsPublic Health +4