Lynne V. Mayne

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

Jaap Venema, L.H.F. Mullenders, A.T. Natarajan et al. · Proceedings of the National Academy of Sciences · 1990 · 556 citations

Life Sciences, Genetics, Molecular Genetics +16

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

Karla A. Henning, Lei Li, Narayan V. Iyer et al. · Cell · 1995 · 505 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Failure of RNA synthesis to recover after UV irradiation; An early defect in cells from individuals with Cockayne syndrome and xeroderma pigmentosum

Lynne V. Mayne, Alan R. Lehmann · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1982 · 420 citations

Life Sciences, Cell Biology, Molecular Biology +12

Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells

Anneke van Hoffen, A.T. Natarajan, Lynne V. Mayne et al. · Nucleic Acids Research · 1993 · 291 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Comparative Human Cellular Radiosensitivity: I. The Effect of SV40 Transformation and Immortalisation on the Gamma-irradiation Survival of Skin Derived Fibroblasts from Normal Individuals and from Ataxia-telangiectasia Patients and Heterozygotes

C.F. Arlett, Michael H.L. Green, Anne Priestley et al. · International Journal of Radiation Biology · 1988 · 140 citations

Medicine, Cell Biology, Dna Repair +14