Wai Lee Wong

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.6K citations

Drug Targeting, Breast Oncology, Disulfide Linkers +12

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

Jagath R. Junutula, Helga Raab, Suzanna Clark et al. · Nature Biotechnology · 2008 · 1.3K citations

Medicinal Chemistry, Immunocytochemical Technique, Drug Targeting +10

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 977 citations

Immunoengineering, Immunology, Bioconjugation +8

Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies

Gail D. Lewis Phillips, Irene S. Figari, B M Fendly et al. · Cancer Immunology Immunotherapy · 1993 · 497 citations · Full text

Anti-p185her2 Monoclonal Antibodies, Medicine, Immunology +9

High Level Escherichia coli Expression and Production of a Bivalent Humanized Antibody Fragment

Paul Carter, Robert F. Kelley, Maria Luı́sa Rodrigues et al. · Nature Biotechnology · 1992 · 330 citations

Engineering, Biotechnology, Synthetic Biology +8