Laurent Désiré

Wnt signalling regulates adult hippocampal neurogenesis

D. Chichung Lie, Sophia A. Colamarino, Hong-jun Song et al. · Nature · 2005 · 1.5K citations

Molecular Neuroscience, Developmental Biology, Hippocampal Neurogenesis +7

Etazolate, a neuroprotective drug linking GABA_A receptor pharmacology to amyloid precursor protein processing

Maryline Marcade, Jérôme Bourdin, Nadia Loiseau et al. · Journal of Neurochemistry · 2008 · 153 citations · Full text

Molecular Pharmacology, Neurodegenerative Diseases, Alzheimer's Disease +15

RAC1 Inhibition Targets Amyloid Precursor Protein Processing by γ-Secretase and Decreases Aβ Production in Vitro and in Vivo

Laurent Désiré, Jérôme Bourdin, Nadia Loiseau et al. · Journal of Biological Chemistry · 2005 · 136 citations · Full text

EHT0202 in Alzheimers Disease: A 3-Month, Randomized, Placebo- Controlled, Double-Blind Study

Bruno Vellas, Olivier Sol, P.- J. Snyder et al. · Current Alzheimer Research · 2011 · 126 citations

A novel DYRK1A (Dual specificity tyrosine phosphorylation‐regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies <i>in vitro</i>

Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde et al. · Journal of Neurochemistry · 2014 · 107 citations