REDD1, a Developmentally Regulated Transcriptional Target of p63 and p53, Links p63 to Regulation of Reactive Oxygen Species

Leif W. Ellisen, Kate D Ramsayer, Cory M. Johannessen, +6

Molecular Cell

Links P63Reductive StressTranscriptional RegulationRedox RegulatorMedicine +8

BMP Type II Receptor Is Required for Gastrulation and Early Development of Mouse Embryos

Hideyuki Beppu, Masahiro Kawabata, Toshiaki Hamamoto, +4

Developmental Biology

Knockout MouseDevelopmental BiologyEarly DevelopmentGeneticsMouse Embryos +7

Histone H3-K9 Methyltransferase ESET Is Essential for Early Development

Jonathan Dodge, Yong‐Kook Kang, Hideyuki Beppu, +2

Molecular and Cellular Biology

Genetic Ablation of the <i>Bmpr2</i> Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension

Kwonho Hong, Young Jae Lee, Eunji Lee, +7

Circulation

Bone Morphogenetic Protein (BMP) Type II Receptor Deletion Reveals BMP Ligand-specific Gain of Signaling in Pulmonary Artery Smooth Muscle Cells

Paul B. Yu, Hideyuki Beppu, Noriko Kawai, +2

Journal of Biological Chemistry

SclerostinImmunologyCellular PhysiologyBone Morphogenetic ProteinSignaling Pathway +16

Increased Susceptibility to Pulmonary Hypertension in Heterozygous BMPR2-Mutant Mice

Yanli Song, John E. Jones, Hideyuki Beppu, +3

Circulation

<i>BMPR-II</i>heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia

Hideyuki Beppu, Fumito Ichinose, Noriko Kawai, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

HypertensionLung InflammationGeneticsImmunologyPulmonary Hypertension +14

Hgs (Hrs), a FYVE Domain Protein, Is Involved in Smad Signaling through Cooperation with SARA

Shigeto Miura, Toshikazu Takeshita, Hironobu Asao, +9

Molecular and Cellular Biology

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice

Yanli Song, Laura A. Coleman, Jianru Shi, +4

American Journal of Physiology-Heart and Circulatory Physiology

Heart FailureInflammatory Lung DiseaseLung InflammationImmunologyEndothelial Injury +15

Bone Morphogenetic Protein (BMP) Type II Receptor Is Required for BMP-mediated Growth Arrest and Differentiation in Pulmonary Artery Smooth Muscle Cells

Paul B. Yu, Donna Y. Deng, Hideyuki Beppu, +5

Journal of Biological Chemistry

Pulmonary Arterial HypertensionDevelopmental BiologyMolecular PhysiologyAngiogenesisSignal Transduction +13