Discovery of 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): A Novel Multimodal Compound for the Treatment of Major Depressive Disorder

Benny Bang‐Andersen, Thomas Ruhland, Morten Jørgensen, +8

Journal of Medicinal Chemistry

Brexpiprazole I: In Vitro and In Vivo Characterization of a Novel Serotonin-Dopamine Activity Modulator

Kenji Maeda, Haruhiko Sugino, Hitomi Akazawa, +14

Journal of Pharmacology and Experimental Therapeutics

Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats

Arne Mørk, Liliana P. Montezinho, Silke Miller, +5

Pharmacology Biochemistry and Behavior

Psychotropic MedicationContextual Fear ConditioningAffective NeurosciencePsychopharmacologySocial Sciences +15

Pharmacological Effects of Lu AA21004: A Novel Multimodal Compound for the Treatment of Major Depressive Disorder

Arne Mørk, Alan L. Pehrson, Lise T. Brennum, +14

Journal of Pharmacology and Experimental Therapeutics

Disruption of Neurogenesis on Gestational Day 17 in the Rat Causes Behavioral Changes Relevant to Positive and Negative Schizophrenia Symptoms and Alters Amphetamine-Induced Dopamine Release in Nucleus Accumbens

Peter Flagstad, Arne Mørk, Birte Glenthøj, +3

Neuropsychopharmacology

Neurobiological MechanismDevelopmental BiologyGestational Day 17PsychiatryBehavioral Neuroscience +12

Stress sensitivity and resilience in the chronic mild stress rat model of depression; an in situ hybridization study

Anders Bergström, M.N. Jayatissa, Arne Mørk, +1

Brain Research

PsychopathologyStress HormonePsychiatryMood SymptomStress +10

The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels

Jacob P. R. Jacobsen, Arne Mørk

Brain Research

Protein ExpressionNeurophysiologyMedicine5-Hiaa LevelsNeuropharmacology +9

A Subpopulation of Neuronal M₄Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors

Jongrye Jeon, Ditte Dencker, Gitta Wörtwein, +11

Journal of Neuroscience

The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats

Arne Mørk, Mads Kreilgaard, Connie Sánchez

Neuropharmacology

NeurophysiologyNeuroanatomyMedicinePhysiologyPsychopharmacology +8

Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Thomas I.F.H. Cremers, Marco Giorgetti, Fokko J. Bosker, +9

Neuropsychopharmacology

Molecular PharmacologyFunctional SelectivityMedicineNeurotransmitterNeuropharmacology +5