A Changing Paradigm for the Treatment of Intermediate-Stage Hepatocellular Carcinoma: Asia-Pacific Primary Liver Cancer Expert Consensus Statements

Masatoshi Kudo, Kwang‐Hyub Han, Sheng-Long Ye, +9

Liver Cancer

Surgical OncologyIntermediate-stage HccPathologyLiver FunctionHepatic Disorders +19

Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice

Hong-Jen Liang, Fat‐Moon Suk, Chung-Kwe Wang, +6

Chemico-Biological Interactions

Metabolic SyndromeBiochemistryLipid NutritionMedicinePhysiology +9

Immunomodulatory activity of dioscorin, the storage protein of yam (Dioscorea alata cv. Tainong No. 1) tuber

Yen-Wenn Liu, Huey-Fang Shang, Chung-Kwe Wang, +2

Food and Chemical Toxicology

BiochemistryPhysiologyStorage ProteinCytoskeletonImmunomodulatory Activity +1

Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer.

Tzu-Ling Tseng, Yi-Ping Shih, Yu-Chuen Huang, +6

PubMed

GeneticsHuman PolymorphismPathologyEpigeneticsTumor Biology +15

Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis

Yi‐Jen Liao, Tzu-Lang Chen, Tzong‐Shyuan Lee, +5

Molecular Medicine

Niemann-Pick type C2 protein regulates liver cancer progression<i>via</i>modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications

Yi‐Jen Liao, Cheng-Chieh Fang, Chia‐Hung Yen, +7

International Journal of Cancer

Primary Hepatocellular CarcinomaFree CholesterolPathologyClinicopathological CorrelationsCancer Biology +22

Niemann-Pick Type C2 Protein Regulates Free Cholesterol Accumulation and Influences Hepatic Stellate Cell Proliferation and Mitochondrial Respiration Function

Yuan-Hsi Wang, Yuh‐Ching Twu, Chung-Kwe Wang, +3

International Journal of Molecular Sciences

Liver FibrosisFree CholesterolPathologyCholangiopathiesOxidative Stress +21

Niemann-Pick Type C2 Protein Mediates Hepatic Stellate Cells Activation by Regulating Free Cholesterol Accumulation

Yuh‐Ching Twu, Tzong‐Shyuan Lee, Yun-Lian Lin, +6

International Journal of Molecular Sciences

Free CholesterolPathologyFatty Liver DiseaseCholangiopathiesCellular Physiology +22

Characterization of Niemann-Pick Type C2 Protein Expression in Multiple Cancers Using a Novel NPC2 Monoclonal Antibody

Yi‐Jen Liao, Meng-Wei Lin, Chia‐Hung Yen, +8

PLoS ONE

ImmunologyPathologyMultiple CancersCancer BiologyTumor Biology +15

Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver

Yi‐Jen Liao, Tzong‐Shyuan Lee, Yuh‐Ching Twu, +5

Journal of Biomedical Science