Berberine inhibits HIF-1alpha expression via enhanced proteolysis.

Shankung Lin, Shiow-Chwen Tsai, Chun-Chung Lee, +3

PubMed

Redox SignalingHif-1alpha ExpressionAngiogenesisBiochemistryHuvec Migration +13

TCF12 Protein Functions as Transcriptional Repressor of E-cadherin, and Its Overexpression Is Correlated with Metastasis of Colorectal Cancer

Chun-Chung Lee, Wei-Shone Chen, Chia-Chi Chen, +4

Journal of Biological Chemistry

Tumor BiologySignal TransductionOncologySignaling PathwayConnexin 26 +12

Secreted Heat Shock Protein 90α (HSP90α) Induces Nuclear Factor-κB-mediated TCF12 Protein Expression to Down-regulate E-cadherin and to Enhance Colorectal Cancer Cell Migration and Invasion

Wei-Shone Chen, Chia-Chi Chen, Li-Li Chen, +2

Journal of Biological Chemistry

Crc PatientsPathologyCancer BiologyTumor BiologyDown-regulate E-cadherin +14

Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs

Chun-Chung Lee, Pey‐Rong Chen, Shankung Lin, +5

Journal of Hypertension

Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells

Chun-Chung Lee, Shu-Chen Chen, Shiow-Chwen Tsai, +4

Journal of Biomedical Science

AngiogenesisVascular AdaptationPhysiologyEndothelial DysfunctionVascular Biology +8

Hypermethylation of the p16 Gene in Sporadic T3N0M0 Stage Colorectal Cancers: Association with DNA Replication Error and Shorter Survival

Jin‐Tung Liang, King‐Jen Chang, Jeng‐Chang Chen, +7

Oncology

GL331 inhibits HIF-1α expression in a lung cancer model

Hang Chang, Kou‐Gi Shyu, Chun-Chung Lee, +4

Biochemical and Biophysical Research Communications

Tumor BiologyMedicineCancer Cell BiologyHif-1α ExpressionCancer Genetics +4

Berberine Inhibits HIF-1α Expression via Enhanced Proteolysis

Shankung Lin, Shiow-Chwen Tsai, Chun-Chung Lee, +3

Molecular Pharmacology

Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity

Kou‐Gi Shyu, Shankung Lin, Chun-Chung Lee, +4

Life Sciences

AngiogenesisEvodiamine InhibitsMedicineVascular BiologyPharmacotherapy +4

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

An Ning Cheng, Shih Sheng Jiang, Chi-Chen Fan, +9

Cancer Letters

Cancer ResearchOncologyCdc7 ContributesMedicineDna-damaging Agents +9