T J Ley

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

Matthew J. Walter, Li Ding, Dong Shen et al. · Leukemia · 2011 · 530 citations

Hematological Malignancy, Chromatin, Medicine +5

The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers

David A. Russler‐Germain, David H. Spencer, Margaret A. Young et al. · Cancer Cell · 2014 · 449 citations · Full text

Cell Regulation, Aml Dominantly, Genetic Disorder +10

Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia

Jeffery M. Klco, David H. Spencer, Chris Miller et al. · Cancer Cell · 2014 · 398 citations · Full text

Hematological Malignancy, Chromatin, Mixed-phenotype Acute Leukemia +7

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

Sujan Shresta, Debra M. MacIvor, Jonathan W. Heusel et al. · Proceedings of the National Academy of Sciences · 1995 · 208 citations · Full text

Radiation Oncology, Cell Signaling, Medicine +15

Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions.

Anne Moon, T J Ley · Proceedings of the National Academy of Sciences · 1990 · 111 citations · Full text

Genetics, Genomic Mechanism, Dna Sequences +24