The MET Receptor Tyrosine Kinase Is a Potential Novel Therapeutic Target for Head and Neck Squamous Cell Carcinoma

Tanguy Y. Seiwert, Ramasamy Jagadeeswaran, Leonardo Faoro, +13

Cancer Research

Tyrosine KinaseCancer BiologyTumor BiologyOncologyReceptor Tyrosine Kinase +15

Activating <i>NOTCH1</i> Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors

Renata Ferrarotto, Yoshitsugu Mitani, Lixia Diao, +17

Journal of Clinical Oncology

Randomized Phase II Study of Bevacizumab in Combination With Chemotherapy in Previously Untreated Extensive-Stage Small-Cell Lung Cancer: Results From the SALUTE Trial

David R. Spigel, P. Townley, David Waterhouse, +7

Journal of Clinical Oncology

Cabozantinib for radioiodine-refractory differentiated thyroid cancer (COSMIC-311): a randomised, double-blind, placebo-controlled, phase 3 trial

Marcia S. Brose, Bruce Robinson, Steven I. Sherman, +12

The Lancet Oncology

Nuclear MedicineMedicineRadionuclide TherapyThyroid DiseasePharmacology +10

Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: A trial of the Chicago, PMH, and California Phase II consortia

Halla Nimeiri, Amit M. Oza, Robert J. Morgan, +7

Gynecologic Oncology

MedicineCancer ManagementGynecologyFallopian Tube CancerImmune Checkpoint Inhibitor +7

Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Ramasamy Jagadeeswaran, Hanna Surawska, Soundararajan Krishnaswamy, +30

Cancer Research

EphA2 Mutation in Lung Squamous Cell Carcinoma Promotes Increased Cell Survival, Cell Invasion, Focal Adhesions, and Mammalian Target of Rapamycin Activation

Leonardo Faoro, Patrick A. Singleton, Gustavo M. Cervantes, +9

Journal of Biological Chemistry

Focal AdhesionsOncologyEpha2 MutationFocal Adhesion AreaMedicine +10

PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription

Rajani Kanteti, Vidya Nallasura, Sivakumar Loganathan, +9

Laboratory Investigation

Tumor BiologyMedicineCancer Cell BiologyTumor SuppressorCancer Genetics +7

The EphB4 Receptor Tyrosine Kinase Promotes Lung Cancer Growth: A Potential Novel Therapeutic Target

Benjamin D. Ferguson, Ren Liu, Cleo E. Rolle, +15

PLoS ONE

Ephb4 InhibitionMedicineReceptor Tyrosine KinaseCancer GrowthCancer Genomics +10

BRIDGE: An Open-Label Phase II Trial Evaluating the Safety of Bevacizumab + Carboplatin/Paclitaxel as First-Line Treatment for Patients with Advanced, Previously Untreated, Squamous Non-small Cell Lung Cancer

John D. Hainsworth, Fang Ting Liang, Jane E. Huang, +4

Journal of Thoracic Oncology

OncologyMetronomic TherapyClinical TrialsBronchial NeoplasmFirst-line Treatment +6