Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin

Kai Kessenbrock, Leopold F. Fröhlich, Michael Sixt, +8

Journal of Clinical Investigation

Lung InflammationImmunologyImmune RegulationCell DeathNeutrophil Infiltration +17

Human Macrophage Metalloelastase. GENOMIC ORGANIZATION, CHROMOSOMAL LOCATION, GENE LINKAGE, AND TISSUE-SPECIFIC EXPRESSION

Azzaq Belaaouaj, J. Michael Shipley, Dale K. Kobayashi, +4

Journal of Biological Chemistry

Myeloperoxidase Plays Critical Roles in Killing <i>Klebsiella pneumoniae</i> and Inactivating Neutrophil Elastase: Effects on Host Defense

Tim O. Hirche, Joseph P. Gaut, Jay W. Heinecke, +1

The Journal of Immunology

Klebsiella PneumoniaeImmunologyInnate Immune SystemCell DeathInnate Immunity +16

Modifying the Protease, Antiprotease Pattern by Elafin Overexpression Protects Mice From Colitis

Jean‐Paul Motta, Laurent Magne, Delphyne Descamps, +17

Gastroenterology

InflammationAnti-inflammatoryMedicineImmunologyGastroenterology +7

Nucleotide sequences of the genes coding for the TEM-like β-lactamases IRT-1 and IRT-2 (formerly called TRI-1 and TRI-2)

Azzaq Belaaouaj, Claudine Lapouméroulie, Maria Manuela Caniça, +4

FEMS Microbiology Letters

Matrix Metalloproteinases Cleave Tissue Factor Pathway Inhibitor: Effects on coagulation

Azzaq Belaaouaj

Journal of Biological Chemistry

InflammationFibrosisMetalloproteinHematologyEndothelial Dysfunction +7

Unopposed Cathepsin G, Neutrophil Elastase, and Proteinase 3 Cause Severe Lung Damage and Emphysema

Nicolas Guyot, Julien Wartelle, Laurette Malleret, +5

American Journal Of Pathology

Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel Function <i>In Vitro</i> and <i>In Vivo</i>

Mathieu Le Gars, Delphyne Descamps, Delphine Roussel, +13

American Journal of Respiratory and Critical Care Medicine

Neutrophil Elastase Mediates Innate Host Protection against <i>Pseudomonas aeruginosa</i>

Tim O. Hirche, Rym Benabid, Gaëtan Deslée, +6

The Journal of Immunology

Neutrophil Elastase Modulates Cytokine Expression

Rym Benabid, Julien Wartelle, Laurette Malleret, +4

Journal of Biological Chemistry

Inflammatory Lung DiseaseMicrobial PathogensLung InflammationInnate Immune SystemImmunology +19