SAHA Enhances Proteostasis of Epilepsy-Associated α1(A322D)β2γ2 GABAA Receptors

Xiao-Jing Di, Dong-Yun Han, Yajuan Wang, +2

Chemistry & Biology

Synaptic PlasticityMolecular NeuroscienceSaha Enhances ProteostasisNeuropharmacologyNeurology +4

Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation

Xiao-Jing Di, Yajuan Wang, Dong-Yun Han, +4

Journal of Biological Chemistry

Protein FunctionSignal TransductionBiochemistryNatural SciencesCell Biology +6

L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABA_A Receptors

Dong-Yun Han, Bo-Jhih Guan, Yajuan Wang, +2

ACS Chemical Biology

Combining Valosin-containing Protein (VCP) Inhibition and Suberanilohydroxamic Acid (SAHA) Treatment Additively Enhances the Folding, Trafficking, and Function of Epilepsy-associated γ-Aminobutyric Acid, Type A (GABAA) Receptors

Dong-Yun Han, Xiao-Jing Di, Yan-Lin Fu, +1

Journal of Biological Chemistry

Synaptic TransmissionNeuromodulation TherapiesMolecular BiologySynaptic SignalingCellular Physiology +27

K+ channel openers restore verapamil-inhibited lung fluid resolution and transepithelial ion transport

Dong-Yun Han, Hong-Guang Nie, Xiu Gu, +6

Respiratory Research

Characterization of a novel splice variant of δ ENaC subunit in human lungs

Runzhen Zhao, Hong-Guang Nie, Xuefeng Su, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

Lung InflammationMolecular Biologyδ Enac SubunitMolecular GeneticsCellular Physiology +21

Cpt-cAMP activates human epithelial sodium channels via relieving self-inhibition

Raúl Reina Molina, Dong-Yun Han, Xuefeng Su, +5

Biochimica et Biophysica Acta (BBA) - Biomembranes

Molecular PhysiologySignal TransductionCell SignalingPhysiologyIon Channels +6

8-pCPT-cGMP stimulates αβγ-ENaC activity in oocytes as an external ligand requiring specific nucleotide moieties

Hong-Guang Nie, Wei Zhang, Dong-Yun Han, +6

American Journal of Physiology-Renal Physiology

Molecular BiologyNeurotransmissionExternal LigandCellular PhysiologyProtein Kinase A +20

Identification of GABA_C Receptor Protein Homeostasis Network Components from Three Tandem Mass Spectrometry Proteomics Approaches

Yajuan Wang, Dong-Yun Han, Tracy Tabib, +2

Journal of Proteome Research

Biological Mass SpectrometryMolecular BiologyBioinformatics AnalysisProteomic TechnologyProteomics +14

8-(4-Chlorophenylthio)-Guanosine-3′,5′-Cyclic Monophosphate-Na Stimulates Human Alveolar Fluid Clearance by Releasing External Na+ Self-Inhibition of Epithelial Na+ Channels

Dong-Yun Han, Hong-Guang Nie, Xuefeng Su, +8

American Journal of Respiratory Cell and Molecular Biology