Karen J. Guarino

Aromatic thiazole derivatives: structurally novel and selective serotonin-3 receptor antagonists

A. Nagel, Terry Rosen, James P. Rizzi et al. · Journal of Medicinal Chemistry · 1990 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Therapeutic Drug Monitoring +13

Structure-activity relationships of 6-(heterocyclyl)-methylene penam sulfones. A new class of .BETA.-lactamase inhibitors.

Yuhpyng L. Chen, Cnm-Wu CHANG, K. HEDBERG et al. · The Journal of Antibiotics · 1987 · 38 citations · Full text

Synthesis, in vitro binding profile, and autoradiographic analysis of [3H]-cis-3-[(2-methoxybenzyl)amino]-2-phenylpiperidine, a highly potent and selective nonpeptide substance P receptor antagonist radioligand

Terry Rosen, Thomas Seeger, Stafford McLean et al. · Journal of Medicinal Chemistry · 1993 · 35 citations · Full text

Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists

Terry Rosen, A. Nagel, J. P. RIZZI et al. · Journal of Medicinal Chemistry · 1990 · 34 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Novel Structural Class +13

Vinyl protecting group for benzimidazole nitrogen: Synthesis of benzimidazole-penam alcohol

Yuhpyng L. Chen, K. HEDBERG, Karen J. Guarino · Tetrahedron Letters · 1989 · 31 citations

Chemical Engineering, Engineering, Organic Chemistry +4