Thomas D. Bethke

Roflumilast—an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial

Klaus F. Rabe, Eric Bateman, Denis O’Donnell et al. · The Lancet · 2005 · 466 citations

Asthma, Inflammation, Antifibrotic Therapy +6

The New Phosphodiesterase 4 Inhibitor Roflumilast Is Efficacious in Exercise‐Induced Asthma and Leads to Suppression of LPS‐Stimulated TNF‐α Ex Vivo

Wolfgang Timmer, V. Leclerc, Guillaume Birraux et al. · The Journal of Clinical Pharmacology · 2002 · 123 citations

Pharmacokinetics of [14C]Ciclesonide After Oral and Intravenous Administration to Healthy Subjects

Ruediger Nave, Thomas D. Bethke, Sjoerd P. van Marle et al. · Clinical Pharmacokinetics · 2004 · 106 citations

Healthy Subjects, Intravenous Administration, Pharmacological Study +4

Two-Dimensional and Three-Dimensional Imaging Show Ciclesonide Has High Lung Deposition and Peripheral Distribution: A Nonrandomized Study in Healthy Volunteers

Chet Leach, Thomas D. Bethke, Robert J. Boudreau et al. · Journal of Aerosol Medicine · 2006 · 90 citations

Asthma, Inflammatory Lung Disease, Advanced Lung Disease +21

Circadian Rhythm of Serum Cortisol after Repeated Inhalation of the New Topical Steroid Ciclesonide

Anita Weinbrenner, Dagny Hüneke, M Zschiesche et al. · The Journal of Clinical Endocrinology & Metabolism · 2002 · 89 citations · Full text