Absolute bioavailability and metabolic disposition of valaciclovir, the L-valyl ester of acyclovir, following oral administration to humans

J Soul-Lawton, Emma J. Seaber, N.T. On, +3

Antimicrobial Agents and Chemotherapy

Pharmaceutical ScienceL-valyl EsterPlasma RadioactivityPharmacological StudyBiochemistry +11

COMPOUNDS DESIGNED TO FIT A SITE OF KNOWN STRUCTURE IN HUMAN HAEMOGLOBIN

C.R. Beddell, P. J. Goodford, F. E. Norrington, +2

British Journal of Pharmacology

Molecular BiologyChemical BiologyRedox BiologyDeoxy ConformationHeme Trafficking +14

Substituted benzaldehydes designed to increase the oxygen affinity of human haemoglobin and inhibit the sickling of sickle erythrocytes

C.R. Beddell, P. J. Goodford, G. KNEEN, +3

British Journal of Pharmacology

Glycyl-<scp>l</scp>-proline transport in rabbit enterocyte basolateral-membrane vesicles

Jane Dyer, R. BRIAN BEECHEY, Jean‐Pierre Gorvel, +3

Biochemical Journal

Proteinlipid InteractionProtein SecretionGlycobiologyCytoskeletonCellular Physiology +19

Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers

R Wootton, J Soul-Lawton, P. Rolan, +3

British Journal of Clinical Pharmacology

High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells

Adrian Newman‐Tancredi, R Wootton, Philip G. Strange

Biochemical Journal

PharmacotherapyExperimental PharmacologyOvarian CancerBovine Hippocampus5-Ht1a Receptor +16

The pharmacokinetics, tolerability and pharmacodynamics of tucaresol (589C80; 4[2‐formyl‐3‐hydroxyphenoxymethyl] benzoic acid), a potential anti‐sickling agent, following oral administration to healthy subjects.

PE Rolan, JE Parker, Gray Sj, +5

British Journal of Clinical Pharmacology

Potential Anti‐sickling AgentHealthy SubjectsPharmacological StudyActive IngredientMedicine +13

Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers

R Wootton, J Soul-Lawton, P. Rolan, +3

British Journal of Clinical Pharmacology

Renal FunctionChronic Renal FailureMedicineHealthy VolunteersChronic Kidney Disease +6

The effects in volunteers of BW12C, a compound designed to left‐shift the blood‐oxygen saturation curve.

Penny Fitzharris, AE McLean, R. Sparks, +3

British Journal of Clinical Pharmacology

Pharmacokinetics and pharmacodynamics of tucaresol, an antisickling agent, in healthy volunteers.

PE Rolan, AJ Mercer, R Wootton, +1

British Journal of Clinical Pharmacology