New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial

Faustino Torrico, Joaquím Gascón, Fabiana Barreira, +33

The Lancet Infectious Diseases

<i>In Vitro</i> Activity of E1210, a Novel Antifungal, against Clinically Important Yeasts and Molds

Mamiko Miyazaki, Takaaki Horii, Katsura Hata, +10

Antimicrobial Agents and Chemotherapy

E1210, a New Broad-Spectrum Antifungal, Suppresses Candida albicans Hyphal Growth through Inhibition of Glycosylphosphatidylinositol Biosynthesis

Naoaki Watanabe, Mamiko Miyazaki, Takaaki Horii, +3

Antimicrobial Agents and Chemotherapy

Microbial PathogensFungal Cell BiologyGlycobiologyNew Broad-spectrum AntifungalClinical Mycology +14

Efficacy of Oral E1210, a New Broad-Spectrum Antifungal with a Novel Mechanism of Action, in Murine Models of Candidiasis, Aspergillosis, and Fusariosis

Katsura Hata, Takaaki Horii, Mamiko Miyazaki, +12

Antimicrobial Agents and Chemotherapy

Oral E1210Antifungal AgentAllergyAntifungal AgentsMedicine +10

GWT1 Gene Is Required for Inositol Acylation of Glycosylphosphatidylinositol Anchors in Yeast

Mariko Umemura, Michiyo Okamoto, Ken-ichi Nakayama, +4

Journal of Biological Chemistry

In vitro and in vivo antifungal activities of ER-30346, a novel oral triazole with a broad antifungal spectrum

Katsura Hata, Junko Kimura, H Miki, +3

Antimicrobial Agents and Chemotherapy

Microbial PathogensMedicinal FungiClinical MycologyAntimicrobial ChemotherapyDermatology +14

Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly

Kappei Tsukahara, Katsura Hata, Kazutaka Nakamoto, +9

Molecular Microbiology

Novel InhibitorGwt1 Gene ProductGlycobiologyMolecular BiologyMedicinal Fungi +16

Efficacy of ER-30346, a novel oral triazole antifungal agent, in experimental models of aspergillosis, candidiasis, and cryptococcosis

Katsura Hata, Junko Kimura, H Miki, +3

Antimicrobial Agents and Chemotherapy

Oral Er-30346Antifungal AgentHealth SciencesAntifungal AgentsMedicine +13

In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution method

Michael A. Pfaller, Katsura Hata, Ronald N. Jones, +3

Diagnostic Microbiology and Infectious Disease

Antifungal AgentAntifungal AgentsCandida SppMedicineBiotechnology +7

Synthesis and evaluation of novel antifungal agents-quinoline and pyridine amide derivatives

Kazutaka Nakamoto, I. TSUKADA, Keigo Tanaka, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryAntifungal AgentDerivativesAntifungal AgentsNovel Antifungal Agents-quinoline +6