Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study

Michael R. McClung, Michelle L. O’Donoghue, Socrates E. Papapoulos, +396

The Lancet Diabetes & Endocrinology

Bone DiseaseOsteopathyLoft Extension StudyMedicineGynecology +8

Concise, Asymmetric Total Synthesis of Spirotryprostatin A

Tomoyuki Onishi, Paul R. Sebahar, Robert M. Williams

Organic Letters

Key StepBioorganic ChemistryHeterocycle ChemistrySingle StepChemical Biology +14

Asymmetric Transfer Hydrogenation of α-Aminoalkyl α‘-Chloromethyl Ketones with Chiral Rh Complexes

Takayuki Hamada, Takayoshi Torii, Tomoyuki Onishi, +2

The Journal of Organic Chemistry

-Diastereomeric AlcoholCross-coupling ReactionAsymmetric Transfer HydrogenationEngineeringQuantitative Yield +11

Concise, asymmetric total synthesis of spirotryprostatin A

Tomoyuki Onishi, Paul R. Sebahar, Robert M. Williams

Tetrahedron

PharmacologyBioorganic ChemistrySpirotryprostatin ANatural Product Synthesis

Synthesis and Antiviral Activity of Novel Anti-VZV 5-Substituted Uracil Nucleosides with a Cyclopropane Sugar Moiety

Tomoyuki Onishi, Chika Mukai, Ryusuke Nakagawa, +9

Journal of Medicinal Chemistry

Vzv Kawaguchi StrainMedicinal Chemistry-5-Halovinyluracil DerivativesAntiviral ActivityMedicine +13

Structure–activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels

Takashi Yamamoto, Seiji Niwa, Seiji Ohno, +12

Bioorganic & Medicinal Chemistry Letters

Structure–activity Relationship StudyIon ChannelsOrganic ChemistryChemistryMedicine +1

Clinico‐pathological aspects of a residual natal tooth: a case report

Hanako Tsubone, Tomoyuki Onishi, Tetsuyuki Hayashibara, +2

Journal of Oral Pathology and Medicine

Practical synthesis of α-aminoalkyl-α′-chloromethylketone derivatives. Part 1: Chloromethylation of N-protected 3-oxazolidin-5-ones

Tomoyuki Onishi, Naoko Hirose, Takashi Nakano, +2

Tetrahedron Letters

Practical SynthesisDerivativesEngineeringN-protected 3-Oxazolidin-5-onesα-Aminoalkyl-α′-chloromethylketone Derivatives +5

Structural Analysis of Unimer Nanoparticles Composed of Hydrophobized Poly(amino acid)s

Phassamon Piyapakorn, Takami Akagi, Masahiro Hachisuka, +3

Macromolecules

NanoparticlesEngineeringNanostructured PolymerPolymer NanocompositesChemistry +17

Practical synthesis of α-aminoalkyl-α′-chloromethylketone derivatives. Part 2: Chloromethylation of N-imine-protected amino acid esters

Tomoyuki Onishi, Takashi Nakano, Naoko Hirose, +2

Tetrahedron Letters

Practical SynthesisDerivativesEngineeringBiochemistryα-Aminoalkyl-α′-chloromethylketone Derivatives +5