J. John Holbrook

A Specific, Highly Active Malate Dehydrogenase by Redesign of a Lactate Dehydrogenase Framework

Helen M. Wilks, Keith Hart, Raymond Feeney et al. · Science · 1988 · 278 citations

Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: Implications for the mechanism of assisted protein folding

Graham S. Jackson, Rosemary A. Staniforth, David Halsall et al. · Biochemistry · 1993 · 263 citations

Equilibrium binding of nicotinamide nucleotides to lactate dehydrogenases

Robert A. Stinson, J. John Holbrook · Biochemical Journal · 1973 · 262 citations · Full text

Ethidium Bromide as a Cooperative Effector of a DNA Structure

Fritz M. Pohl, Thomas M. Jovin, Wolfgang Baehr et al. · Proceedings of the National Academy of Sciences · 1972 · 202 citations · Full text

Dna, Genetics, Dna Analysis +16

Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis

Anthony R. Clarke, Dale B. Wigley, William Chia et al. · Nature · 1986 · 178 citations

Biochemistry, Natural Sciences, Enzyme Catalysis +4