Taxane-Induced Blockade to Nuclear Accumulation of the Androgen Receptor Predicts Clinical Responses in Metastatic Prostate Cancer

Medha S. Darshan, Matthew S. Loftus, Maria Thadani‐Mulero, +10

Cancer Research

Cancer BiologyTumor BiologyMetastatic Prostate CancerGenitourinary CancerCancer Cell Biology +16

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling

Makoto Sumitomo, Ruoqian Shen, Marc Walburg, +8

Journal of Clinical Investigation

Transdifferentiation of cultured human prostate cancer cells to a neuroendocrine cell phenotype in a hormone-depleted medium

Ruoqian Shen, Thambi Dorai, Matthias Szaboles, +3

Urologic Oncology Seminars and Original Investigations

Synergy in tumor suppression by direct interaction of Neutral Endopeptidase with PTEN

Makoto Sumitomo, Akira Iwase, Rong Zheng, +5

Cancer Cell

Protein FunctionSignal TransductionMedicineTumor SuppressionDirect Interaction +8

Identification and characterization of two androgen response regions in the human neutral endopeptidase gene

Ruoqian Shen, Makoto Sumitomo, Jie Dai, +7

Molecular and Cellular Endocrinology

Endocrine MechanismMedicineGeneticsNatural SciencesHormonal Receptor +9

The emergence of protocadherin-PC expression during the acquisition of apoptosis-resistance by prostate cancer cells

Min‐Wei Chen, Francis Vacherot, Alexandre de la Taille, +6

Oncogene

MedicineApoptosisCell DeathProstate Cancer CellsTumor Suppressor +9

Androgen-Induced Growth Inhibition of Androgen Receptor Expressing Androgen-Independent Prostate Cancer Cells Is Mediated by Increased Levels of Neutral Endopeptidase*

Ruoqian Shen, Makoto Sumitomo, Jie Dai, +5

Endocrinology

Androgen ReceptorSignal TransductionEndocrine-related CancerBiochemistryMedicine +13

Neprilysin Inhibits Angiogenesis via Proteolysis of Fibroblast Growth Factor-2

Oscar B. Goodman, Maria Febbraio, Ronit Simantov, +4

Journal of Biological Chemistry

Bombesin attenuates pre-mRNA splicing of glucocorticoid receptor by regulating the expression of serine-arginine protein p30c (SRp30c) in prostate cancer cells

Jin Zhu, Jun Y. Gong, Oscar B. Goodman, +3

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Systems BiologyHormonal ReceptorGene ExpressionProstate Cancer CellsSerine-arginine Protein P30c +7

Neutral endopeptidase promotes phorbol ester-induced apoptosis in prostate cancer cells by inhibiting neuropeptide-induced protein kinase C delta degradation.

Makoto Sumitomo, Ruoqian Shen, Jonathan S. Goldberg, +3

PubMed

Chemoprevention StrategyApoptosisCell DeathProstate Cancer CellsPkcdelta Protein +18