Structure of the Rat Interleukin 6 Gene and Its Expression in Macrophage-derived Cells

W Northemann, T A Braciak, Masahira Hattori, +2

Journal of Biological Chemistry

ImmunologyImmune RegulationImmunologic MechanismMacrophage-derived CellsImmune System +14

Sequence of rat liver alpha 2-macroglobulin and acute phase control of its messenger RNA.

Brian Shiels, W Northemann, M H de Bruijn, +4

Journal of Biological Chemistry

Laboratory ImmunologyImmunologyPathologyAlpha 2-Macroglobulin GeneAcute Phase Control +19

Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene.

Masahira Hattori, L J Abraham, W Northemann, +1

Proceedings of the National Academy of Sciences

2-Macroglobulin GeneImmunologyImmune RegulationCell DeathImmunologic Mechanism +18

Simplified northern blot hybridization using 5% sodium dodecyl sulfate.

G. Duke Virca, W Northemann, Brian Shiels, +2

PubMed

EngineeringGeneticsMany ReagentsMolecular BiologyMolecular Genetics +14

IL-6 functions as an exocrine hormone in inflammation. Hepatocytes undergoing acute phase responses require exogenous IL-6.

Jack Gauldie, W Northemann, G H Fey

The Journal of Immunology

Rat Il-6Il-6 FunctionsImmunologyImmune SystemInflammation +20

IFN beta 2/BSF2/IL-6 is the monocyte-derived HSF that regulates receptor-specific acute phase gene regulation in hepatocytes.

Jack Gauldie, Carl D. Richards, W Northemann, +2

PubMed

InflammationCytokineHepatologyLiver PhysiologyImmune Regulation +10

Molecular cloning of cDNA sequences for rat alpha 2-macroglobulin and measurement of its transcription during experimental inflammation.

W Northemann, Michael Heisig, Dieter Kunz, +1

Journal of Biological Chemistry

Immune RegulationImmunologyTurpentine AdministrationInflammationProtein Expression +14

Modified nuclear processing of alpha 1-acid glycoprotein RNA during inflammation.

Brian Shiels, W Northemann, G H Fey

Journal of Biological Chemistry

Prevalence of autoantibodies to the 65- and 67-kD isoforms of glutamate decarboxylase in insulin-dependent diabetes mellitus.

Josef Amann, Ludwig Mauch, Heinz Haubruck, +6

Journal of Clinical Investigation

Autoimmune DiseaseBiochemistryInsulin-dependent Diabetes MellitusSera Gad65Iddm Antibodies +13

Induction of rat α₂‐macroglobulin in vivo and in hepatocyte primary cultures: synergistic action of glucocorticoids and a Kupffer cell‐derived factor

Joachim Bauer, M. Birmelin, Gerd-Hinrich Northoff, +5

FEBS Letters